Archive for Allopathy

The entire vaccine program is based on a massive Fraud.

blaylock

Post Vaccination – Vaccine Targeted Strain – Viral and Bacterial Pathogen – Shedding

So how much of this said claim is truth and real, and/or not real? Do we know? A search for the evidence.

First of all, let me ask this. Why is it, that when the conclusions of actually peer reviewed studies are not in your favor as to the intended agenda bias, that even endless peer reviewed studies are not enough to get pro-vaccine people to take a look at and even read a single one of those studies; yet when there are limited to little to no existing peer reviewed studies, that they are jumping all over with demands to produce a peer reviewed study, to make such as any certain such as a vax-truth opposing persons point of contention, that has expressed?

In regard to vaccines lets go to the issue of vaccine shedding, and ask the question as to can and do any of the current vaccines shed the pathogen in a way that could make a non vaccinated person susceptible to acquiring the illness from a vaccinated person. There are in Pubmed several but limited studies that address the shedding issue as to in regard to the various vaccines. Just use the search terms vaccine shedding Pubmed, and will you several but as said limited numbers references in the google listing, and then you can go to pubmed itself, which is somewhat as well limited for available references as to claiming one way or the other. As for the measles vaccine, one Pubmed reference stated that it the vaccine could shed for up to three days. Certainly long enough to infect another individual.

So, actually and possibly no one really nor likely knows for sure what the complete truth is on this issue. It would seem to be common sense that the vaccine makers surely do not and would not want to know if their vaccine causes shedding or not; nor to find out. So then who would actually fund theses said studies. I think with what I read and reviewed in regard to vaccine shedding, just getting into even the beginning phase of the studies, tells me that vaccines do have a potential to shed irregardless of being bacterial or viral; which very well could be an obvious risk to the unvaccinated. I mean good grief, the existing studies clearly point to the push to vaccinate everyone due to the risk of shedding possibility. What more evidence would you need of the risk of the vaccinated, to the unvaccinated? And yet the pro-vaccine side wants to claim to just the opposite; and that it is only the vaccinated that are at risk from the unvaccinated??? You know accused again of reducing the vaccine derived herd immunity; even though the schools most often even today have no more than a 5% or less rate of existing school exemptions?  We as well by the way are not are NOT just talking about the oral polio vaccine, here. They clearly know that the oral polio vaccine sheds and can as well cause numerous cases of AFP in the underdeveloped and unsanitary for conditions countries, that the oral polio vaccine is still used to day. They know of the identified mutations in the polio vaccine virus that the the said oral vaccine has very likely as well caused. if they have an alternative explanation, I have yet to hear and or read about it.

So, let me ask you, have vaccines eradicated so called illness and disease, or have they just prolonged the exit, while creating only lower levels of chronic disease, and disease conditions? How about other unrelated chronic illness and autoimmune disease, unrelated to the vaccine targeted pathogen? How about the pubmed listed as well references to the harm of aluminum adjuvants, causing overactivation of the brains microglia and resulting low levels of chronic brain inflammation resulting for repeat multiple vaccines, in some individuals; maybe more individuals and children that we have ever realized? How about the aluminum adjuvant connection to ASD? The studies, and new studies have shown that same brain inflammation to now be found in more and more children and individuals with ASD. And they want to tell us that vaccines have never been scientifically linked in any study, to ASD? Really? How about the MMR vaccine, in which there are actually some similar physiological pathways found in relation to ASD, and also which are in common with heavy metal toxicity, if not overload, in regard to both thimerosal, and aluminum adjuvants. I don’t know about you and what you think, but I think it is not looking good for the claim as to the issue of vaccines doing more good than harm. When will the CD stop living in the dark ages, and dragging their feet as to doing the proper studies? Yet they waste millions chasing the genetic link to ASD, and refuse all other types and forms of real research?

I did pick one specific peer reviewed reference in regard shedding, that I thought was interesting, and a bit troublesome regarding risk. In regard to the shedding of course all they can come up with is to come up with that every last person existing must be vaccinated to protect them against the shedding.

Pertussis infection in fully vaccinated children in day-care centers, Israel.

Abstract

We tested 46 fully vaccinated children in two day-care centers in Israel who were exposed to a fatal case of pertussis infection. Only two of five children who tested positive for Bordetella pertussis met the World Health Organization’s case definition for pertussis. Vaccinated children may be asymptomatic reservoirs for infection.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627963/

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627963/pdf/10998384.pdf

Pertussis Vaccine Failure is not Just Modern but Historical: Vaccine has Never Been Effective
http://healthimpactnews.com/2013/pertussis-vaccine-failure-is-not-just-modern-but-historical-vaccine-has-never-been-effective/

Researchers find first US evidence of vaccine-resistant pertussis
http://healthimpactnews.com/2013/researchers-find-first-us-evidence-of-vaccine-resistant-pertussis/

And they tell us the vaccines do not shed? How would this be possible if the vaccines do not shed anything contagious? And they want us to believe that the un-vaccinated are a risk to the vaccinated. Vaccine derived herd relatively and comparatively short term immunity, has never had any actual science behind it; and as to natural long term and/or life time immunity, where as that concept actually makes does sense. So what is the REAL reason they say they need vaccine derived herd immunity? Is it possible that it is more likely due to the issue of vaccine shedding? Now we are getting to some actual understanding of what possibly really goes on.

17 Examples of Admitted Vaccine Failure
http://vactruth.com/2013/02/23/17-examples-of-vaccine-failure/

Article

ECZEMA VACCINATUM

ABSTRACT

Nine cases of eczema vaccinatum are presented, including two fatalities. Seven were caused by contact of a child with eczema with a recently vaccinated sibling.

Suddenly appearing umbilicated vesicles superimposed upon atopic eczema are almost diagnostic of eczema vaccinatum or eczema herpeticum. These do not occur with mere secondary bacterial infection.

Hyperimmune vaccinal gamma-globulin is now available for specific therapy.

Eczema vaccinatum is frequently iatrogenic and uniformly preventable.

The following steps are recommended for prophylaxis: 1) No child with atopic eczema or other skin disorder should be vaccinated. 2) No child should be vaccinated if any member of his family has eczema or other skin disorder. 3) Parents of children with eczema should be notified at the onset of the disease of the danger from vaccination contact. 4) If a sibling of a child with atopic eczema is vaccinated, he must be completely separated from that child for at least 21 days. 5) Forms used by state and local health departments for parents’ consent to vaccination should include an appropriate warning of the contraindications. 6) Eczema vaccinatum should be a reportable disease. 7) Patients recently vaccinated must be excluded from pediatric wards containing patients with atopic eczema, other diseases of the skin, burns or healing surgical incisions. 8) Vaccination may be recommended at 2 months of age, especially for babies from strongly allergic families.

http://pediatrics.aappublications.org/content/22/2/259

Acellular pertussis vaccination enhances B. parapertussis colonization

An acellular whooping cough vaccine actually enhances the colonization of Bordetella parapertussis in mice; pointing towards a rise in B. parapertussis incidence resulting from acellular vaccination, which may have contributed to the observed increase in whooping cough over the last decade.

http://www.cidd.psu.edu/research/synopses/acellular-vaccine-enhancement-b.-parapertussi

And rarely are they testing for it nor even knowing understanding what pertussis pathogen strains are there. B parapertussis antigen is not in the current vaccine. And the fear mongering and the recommended boosters continue.

They can admit to the pertussis vaccine failure in Pakistan, but the CDC can not and refuses to admit to that here happening in the US.

Public Health. 2012 Jun;126(6):518-22. doi: 10.1016/j.puhe.2012.02.001. Epub 2012 Mar 23.

Pertussis resurgence among vaccinated children in Khairpur, Sindh, Pakistan.

Mughal A, Kazi YF, Bukhari HA, Ali M.

Source:Diagnostic and Research Centre, Department of Microbiology, Shah Abdul Latif University, Khairpur, Sindh, Pakistan.

Abstract

OBJECTIVES:

To investigate the aetiology of persistent cough among vaccinated children as suspected cases of pertussis in Khairpur District, Sindh, Pakistan. Pertussis or whooping cough, caused by Bordetella pertussis, is re-appearing in many countries despite vaccination coverage. In Khairpur, persistent cough and symptoms similar to pertussis among vaccinated children are common but the aetiology has not been investigated previously.

STUDY DESIGN:

B. pertussis was isolated from cough samples of suspected pertussis patients (n = 700) using the cough plate method with charcoal agar.

METHODS:

Isolation and confirmation of the clinical isolates of B. pertussis was performed by culture on Bordet-Gengou medium, biochemical tests and polymerase chain reaction.

RESULTS:

In total, 22 strains of B. pertussis were isolated from clinical cough samples.

CONCLUSION:

To the authors’ knowledge, this is the first report of the presence of pertussis in vaccinated children in Khairpur. There is a need for continuous monitoring of pertussis after immunization programmes in order to assess the efficacy of pertussis vaccination.

http://www.ncbi.nlm.nih.gov/pubmed/22445714

And what has the CDC done about it all? They have only continued with their fear mongering and falsely blaming the un-vaccinated. Cocoon tyle vaccinating whole families, and still the outbreaks occur.

The False Theory of Vaccine Derived – Herd Immunity 
http://www.vacfacts.info/the-false-theory-of-vaccine-derived—herd-immunity.html

———————-

Whooping Cough Epidemic Caused by Virulent New Pertussis Strain—And It’s the Result of Vaccine
http://gaia-health.com/gaia-blog/2012-10-31/whooping-cough-epidemic-caused-by-virulent-new-pertussis-strain-and-its-the-result-of-vaccine/

Bordetella pertussis Strains with Increased Toxin Production Associated with Pertussis Resurgence (PDF)

Abstract excerpt:

We present evidence that in the Netherlands the dramatic increase in pertussis is temporally associated with the emergence of Bordetella pertussis strains carrying a novel allele for the pertussis toxin promoter, which confers

increased pertussis toxin (Ptx) production. Epidemiologic data suggest that these strains are more virulent in humans. We discuss changes in the ecology of B. pertussis that may have driven this adaptation. Our results underline the importance of Ptx in transmission, suggest that vaccination may select for increased virulence, and indicate ways to control

http://gaia-health.com/articles451/000485-bpertussis.pdf

J Hyg (Lond). 1976 August; 77(1): 85–91.

PMCID: PMC2129724

Prevalent serotypes of Bordetella pertussis in non-vaccinated communities.

Abstract

In many countries, the prevalent serotypes of Bordetella pertussis have changed from a mixture of types 1,2,3 and 1,2 (organisms possessing antigen 2) to a predominance of type 1,3. The timing of the change in different countries is shown to be related to the introduction of mass-vaccination with material rich in antigens 1 and 2 but weak in, or devoid of, antigen 3. In several parts of the world, there have been outbreaks of type 1,3 infection in fully vaccinated children. Non-vaccinated communities in various parts of the world still show the pattern of serotypes which existed elsewhere before mass-vaccination. In order to avoid the disappointments experienced in the past, it is essential that pertussis vaccine for use in previously non-vaccinated communities, like that for any other country, should be rich in each of the three antigens.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2129724/

RESEARCH ARTICLE

Small Mutations in Bordetella pertussis Are Associated with Selective Sweeps

Abstract excerpt:

Our results suggest that the B. pertussis gene repertoire is already well adapted to its current niche and required only fine tuning to persist in the face of vaccination. Further, this work shows that small mutations, even single SNPs, can drive large changes in the populations of bacterial pathogens within a time span of six to 19 years.

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0046407

You can not patent vitamin C, as you can an expensive drug or vaccine. Modern medicine is NOT about the actual health of your child, unless it can be done with chemical pharma.

Special Report: The Vitamin C Treatment of Whooping Cough (Pertussis)

http://www.vaccinationcouncil.org/2011/12/20/special-report-the-vitamin-c-treatment-of-whooping-cough-suzanne-humphries-md/

Here is what they already knew years ago in the treatment of pertussis.

Can Med Assoc J. 1937 August; 37(2): 134–136.
PMCID: PMC1562195
Ascorbic Acid (Vitamin C) Treatment of Whooping Cough *

Discussion
The short series of cases presented is too small to draw any statistical conclusions, but one fact stands out. Ascorbic acid has a definite efTect in shortening the period of paroxysms from a matter of weeks to a matter of days. We have not checked by cough plates or otherwise in this preliminary work to see whether the infectivity subsides simultaneously with the spasmodic symptoms, but are continuing with a larger series of cases in which these and other tests will be employed.

The dosages used have been empirical, with a tendency to use larger doses early in the disease as our experience of its effects progressed. The acid is available at reasonable prices, and the danger of overdosage seems negligible. Animals have received 2,000 times their estimated requirements without any deleterious effects. Any excess is excreted by the kidneys.

CONCLUSIONS
1. A method has been described for the treatment of whooping cough by ascorbic acid
(vitamin C).
2. Ascorbic acid definitely shortens the paroxysmal stage of the disease, particularly if
relatively

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562195/?page=3

Pertussis is a bacteria, but either way it is beneficial.

Vitamin C As An Antiviral: It’s All About Dose

http://orthomolecular.org/resources/omns/v05n09.shtml

Vitamin C for Whooping Cough. Updated Edition. Suzanne Humphries, MD
http://www.vaccinationcouncil.org/2012/09/07/vitamin-c-for-whooping-cough-updated-edition-suzanne-humphries-md/

Why is nobody studying vitamin C in whooping cough? – Conventional medicine’s hypocrisy. by Suzanne Humphries, MD
http://www.vaccinationcouncil.org/2012/08/03/why-is-nobody-studying-vitamin-c-in-whooping-cough-by-suzanne-humphries-md/

LIPOSOMAL ENCAPSULATED VITAMIN C
http://www.vacfacts.info/anti-viral—liposomal-encapsulated-vitamin-c.html

————————————-

History Repeats Itself: Lessons Vaccinators Refuse to Learn, by Jennifer Craig, PhD
http://www.vaccinationcouncil.org/2012/04/17/history-repeats-itself-lessons-the-vaccinationists-refuse-to-learn-by-jennifer-craig-phd/

Another below is another example of a failed effort with polio vaccine. It does little good to claim to have eliminated a certain number of previously present cases of polio, while at the same time causing massive cases of polio vaccine derived paralysis. 47,500 new cases. Yet they claim this is NECESSARY, to eradicate polio. They refuse to admit any failure, it seems to me?

Indian J Med Ethics. 2012 Apr-Jun;9(2):114-7.

Polio programme: let us declare victory and move on.

Vashisht N, Puliyel J.

Source:Department of Paediatrics, St Stephens Hospital, Delhi 110054, India.

Abstract

It was hoped that following polio eradication, immunisation could be stopped. However the synthesis of polio virus in 2002, made eradication impossible. It is argued that getting poor countries to expend their scarce resources on an impossible dream over the last 10 years was unethical. Furthermore, while India has been polio-free for a year, there has been a huge increase in non-polio acute flaccid paralysis (NPAFP). In 2011, there were an extra 47,500 new cases of NPAFP. Clinically indistinguishable from polio paralysis but twice as deadly, the incidence of NPAFP was directly proportional to doses of oral polio received. Though this data was collected within the polio surveillance system, it was not investigated. The principle of primum-non-nocere was violated. The authors suggest that the huge bill of US$ 8 billion spent on the programme, is a small sum to pay if the world learns to be wary of such vertical programmes in the future.

http://www.ncbi.nlm.nih.gov/pubmed/22591873

VIDS – Vaccine Induced Diseases
http://www.vaccinesuncensored.org/vids.php

51 035 cases of AFP appear in this document (p 578) for India in 2011, and the in 2011. The figure of 86 638 cases of AFP was listed as globally.

http://www.who.int/wer/wer8650.pdf

VRM: The Re-emergence of Polio in The Third World (compliments of the World Health Organization & Bill Gates)
http://vaccineresistancemovement.org/?p=10091

VRM: Weaponized Polio & The African Green Monkey Conundrum
http://vaccineresistancemovement.org/?p=10727

Why I choose not to Vaccinate my child
by: Amy Goalen Whittam
https://docs.google.com/document/pub?id=1Y2hS7WxS2gU4yXCjuYx84AY60tQc2rGXnTPPWqogOfk

What Is Coming Through That Needle? The Problem of Pathogenic Vaccine Contamination

Benjamin McRearden

http://www.scribd.com/doc/42722540/Vaccine-Contamination-Mcrearden

Mutant Polio Virus Spreads in Nigeria

Experts have long believed epidemics unleashed by a vaccine’s mutated virus wouldn’t last since the vaccine only contains a weakened virus strain – but that assumption is coming under pressure. Some experts now say that once viruses from vaccines start circulating they can become just as dangerous as wild viruses.

“The only difference is that this virus was originally in a vaccine vial,” said Olen Kew, a virologist at the U.S. Centers for Disease Control and Prevention.

The oral polio vaccine used in Nigeria and elsewhere contains a mild version of the live virus. Children who have been vaccinated pass the virus into the water supply through urine or feces. Other children who then play in or drink that water pick up the vaccine’s virus, which gives them some protection against polio.

But in rare instances, as the virus passes through unimmunized children, it can mutate into a strain dangerous enough to ignite new outbreaks, particularly if immunization rates in the rest of the population are low.

Kew said genetic analysis proves mutated viruses from the vaccine have caused at least seven separate outbreaks in Nigeria.

Though Nigeria’s coverage rates have improved, up to 15 percent of children in the north still haven’t been vaccinated against polio. To eradicate the disease, officials need to reach about 95 percent of the population.

Nigeria’s vaccine-linked outbreak underlines the need to stop using the oral polio vaccine as soon as possible, since it can create the very epidemics it was designed to stop, experts say. WHO is researching other vaccines that might work better, but none is on the horizon.

Until a better vaccine is ready, WHO and U.S. CDC officials say the oral vaccine is the best available tool to eradicate polio and that when inoculation rates are nearly 100 percent it works fine.

“Nigeria is almost a case study in what happens when you don’t follow the recommendations,” Kew said.

http://www.cbsnews.com/2100-204_162-5242168.html

Mutated Polio From Vaccine Is Spreading in Africa

A mutation from a live polio vaccine is stalking Nigeria. In a strange twist of logic, experts are claiming that it mutated as it passed through non-immunized children.

The claim is that children given the live attenuated oral vaccine are properly immunized, but the live virus passes through them and enters local water supplies through their urine or feces. Then, children who have not been immunized pick up the supposedly safe virus by drinking or playing in the water. The weakened virus mutates in them, becoming a new virulent strain.

Why the virus would choose to mutate in non-vaccinated, rather than vaccinated, children is unexplained. Even odder is why the weakened virus would pass through the vaccinated children. If the purpose of a live attenuated vaccination is to force the body to develop antibodies to the virus, then why would live viruses be excreted? Shouldn’t they be killed by the newly-developed antibodies?

Are we being lied to?

This sounds much like the argument that blames nonvaccinated people for disease in those who’ve submitted to innoculations. If the vaccines are effective, then why would the vaccinated be at risk from the unvaccinated?

Are we being lied to?

http://www.gaia-health.com/articles51/000078-Polio-Caused-By-Vaccine.shtml

Nigeria Sees Polio Outbreak from Mutated Vaccine Virus
http://www.pbs.org/newshour/updates/health/july-dec09/polio_08-24.html

Polio in Nigeria Traced to Mutating Vaccine
http://www.nytimes.com/2007/10/11/world/africa/11polio.html?_r=0

Mutated virus confirms polio vaccine fears. New Delhi
http://www.telegraphindia.com/1101024/jsp/nation/story_13094132.jsp

Vaccine. 1994 May;12(6):503-7.

Point mutations involved in the attenuation/neurovirulence alternation in type 1 and 2 oral polio vaccine strains detected by site-specific polymerase chain reaction.

We screened for this mutation in five type 1 and nine type 2 polio vaccine-derived strains isolated from vaccine-associated paralytic poliomyelitis (VAPP) cases and in 16 such strains isolated from healthy vaccinees. All 14 strains isolated from VAPP presented the reversion. Of the eight pairs of type 1 isolates from healthy vaccinees, four presented the reversion 3 days after vaccine administration and all but one at 7 days postvaccination. These results support the involvement of the 5′ non-coding specific nucleotide sites in the reversion to neurovirulence of attenuated polio vaccine strains upon multiplication in the human gut

http://www.ncbi.nlm.nih.gov/pubmed/8036823

Look at the unbelievable statements in the next set of information. So ask, WHY are they using a live and shedding viral vaccine, in these contaminated areas, at all?

Oral Polio Vaccine Circulation and Mutation after Mexican National Immunization Weeks

Conclusion: OPV, primarily serotype 2, was detected in sewage as late as 7 months after an NIW in a Mexican community primarily vaccinated with IPV, but was not detected at 8 months, suggesting that OPV circulation may have ceased.  VAPP mutants were predominantly detected.  This data suggests that in communities with high vaccination rates, one or two years of IPV administration after OPV cessation could be sufficient to prevent outbreaks of paralytic poliomyelitis from vaccine-derived strains.

https://idsa.confex.com/idsa/2011/webprogram/Paper30468.html

Polio vaccine suspected as cause of fatal mutant form of encephalitis

The polio vaccine isn’t protecting children – and, worse, it appears to be causing a new and sometimes fatal form of the disease.

Concerns about the vaccine have arisen following a high number of deaths and hospital admissions from encephalitis and polio in the Uttar Pradesh region of India – where there has been an intensive vaccination programme.

Around 400 children have died, and a further 2,300 admitted to hospital, following an outbreak of a new form of viral encephalitis, and doctors admit they do not know its cause.

http://www.wddty.com/polio-vaccine-suspected-as-cause-of-fatal-mutant-form-of-encephalitis.html

Unvaccinated Blamed for Mutated Polio, (AGAIN ALWAYS FALSELY THE UNVACCINATED ARE BLAMED FOR ANYTHING THAT HAPPENS)

Mutant polio vaccine regains virulence

Excerpts:

But the latest study raises the frightening possibility that the vaccine strain can also regain the ability to spread between people more easily than thought. “It demonstrates clearly that the vaccine virus can spread from person to person,” says Olen Kew from the Centers for Disease Control and Prevention in Atlanta, Georgia.

The outbreak was exacerbated by the fact that Haiti had relaxed its polio vaccination program more than five years earlier. “It’s a warning that you need to have good coverage to prevent vaccines from running away like this,” Kew says.

Total eradication

The study also shows how difficult it will be eliminate polio entirely. For this to be achieved, natural polio would first have to be wiped out through stringent use of the oral polio vaccine. Then all countries could simultaneously stop vaccinating or switch to a different vaccine – injectable, dead polio virus.

This method does not confer as much immunity as the oral vaccine, but it cannot revert to a disease-causing form. This vaccine is already used in the US and much of Europe.

http://www.newscientist.com/article/dn2047-mutant-polio-vaccine-regains-virulence.html

This again points to the claim that they think they need to get 100% vaccine coverage in ever country with existing polio, and only then it may be possible to stop polio, but yet they know they will have the mutations still going on and the result of that is in their minds quite obviously only necessary collateral damage, so to speak. So, as long as they can keep blaming it all on the unvaccinated, which is not exactly proven; it is an assumption. And as long as they keep playing Russian Roulette with the vaccine virus; in the hopes that it does not continue to mutate to a point of becoming a super virus world wide. But in the end, the with the known odds that have been and in the resulting outcomes; clearly it all shows this plan to be not only failing and dangerous; but even currently, is likely causing more harm than good; and will continue to.

J Clin Microbiol. 1995 Sep;33(9):2485-8.

Detection of measles virus RNA in urine specimens from vaccine recipients.

Rota PA, Khan AS, Durigon E, Yuran T, Villamarzo YS, Bellini WJ.

Source: Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

Abstract

Analysis of urine specimens by using reverse transcriptase-PCR was evaluated as a rapid assay to identify individuals infected with measles virus. For the study, daily urine samples were obtained from either 15-month-old children or young adults following measles immunization. Overall, measles virus RNA was detected in 10 of 12 children during the 2-week sampling period. In some cases, measles virus RNA was detected as early as 1 day or as late as 14 days after vaccination. Measles virus RNA was also detected in the urine samples from all four of the young adults between 1 and 13 days after vaccination. This assay will enable continued studies of the shedding and transmission of measles virus and, it is hoped, will provide a rapid means to identify measles infection, especially in mild or asymptomatic cases.

http://www.ncbi.nlm.nih.gov/pubmed/7494055

You see in the next below link that it ALL depends on who has done the study, as for if they find the evidence of shedding due to a/or the vaccine. Here we have the Journal of Infectious diseases that is closely aligned with pharma and Offit’s CHOP. And they of course find predicable no shedding. Can you imagine the upset if they had, and presented to the CDC with that? Clearly, is not happening.

J Infect Dis. 2004 May 1;189 Suppl 1:S165-70.

Lack of evidence of measles virus shedding in people with inapparent measles virus infections.

http://www.ncbi.nlm.nih.gov/pubmed/15106106

And here, and again pharma connected

http://www.ncbi.nlm.nih.gov/pubmed/22983013

So, the pro vaccine side again claims to what? Well if there are no studies to prove that the vaccines cause shedding, then it simply doesn’t happen. Just like in regard to the vaccine aluminum adjuvants; if no studies have ever been done, then we can proclaim that there is no scientific proof of the harm, thus there is no said harm being done.

J Clin Microbiol. 2008 Mar;46(3):1101-3. Epub 2008 Jan 9.

Detection of RNA of mumps virus during an outbreak in a population with a high level of measles, mumps, and rubella vaccine coverage.

Bitsko RH, Cortese MM, Dayan GH, Rota PA, Lowe L, Iversen SC, Bellini WJ.

Source:Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

Abstract

The duration of mumps virus RNA detection was studied during a mumps outbreak in a highly vaccinated university population. Seven of the eight reverse transcription-PCR-positive specimens were collected during the first 3 days of parotitis, suggesting that viral shedding is minimal after the first 3 days of symptoms.

http://www.ncbi.nlm.nih.gov/pubmed/18184850

However, in three days, you could infect 100′s of people.

General Index: But as you can see, very few actual studies on vaccine shedding have been done.

http://www.ncbi.nlm.nih.gov/pubmed?term=shedding%20of%20measles%20vaccine%20mealses

http://www.ncbi.nlm.nih.gov/sites/entrez

Secondary Transmission: The short and sweet about live virus vaccine shedding.(A short list of the evidence of shedding in regard to each specific vaccine).

http://insidevaccines.com/wordpress/2008/02/24/secondary-transmission-%EF%BB%BFthe-short-and-sweet-about-live-virus-vaccine-shedding/

Measles Vaccine Found in Throat of Vaccinated Child
http://www.ncbi.nlm.nih.gov/pubmed/11858860

Pediatr Dermatol. 2005 Mar-Apr;22(2):130-2.

Vaccine-associated “wild-type” measles.
http://www.ncbi.nlm.nih.gov/pubmed/15804301

Acta Paediatr Jpn. 1995 Jun;37(3):374-6.
Measles encephalomyelitis in a patient with a history of vaccination.

http://www.ncbi.nlm.nih.gov/pubmed/7645392

Clin Infect Dis. 1999 Oct;29(4):855-61.
Measles inclusion-body encephalitis caused by the vaccine strain of measles virus.
http://www.ncbi.nlm.nih.gov/pubmed/10589903

Pediatr Neurol. 1999 May;20(5):399-402.

Acute disseminated encephalomyelitis with probable measles vaccine failure.
http://www.ncbi.nlm.nih.gov/pubmed/10371390

I would take my chances with natural infection and recovery, any day; over that of the use of a vaccine, or in this and the most common case, the MMR vaccine..

Picture

Free Speech Rights Under Attack in Australia

Free Speech Rights Under Attack in Australia

March 29, 2013 by admin in Featured, Politics, Vaccines with 0 Comments

Whatever you believe about vaccination, surely those who disagree with forced inoculations and medical treatment have the right to their views and to choose whether they’ll be subjected to medical treatments of any sort, including vaccination. But the right is under siege in Australia, as the Australian Vaccination Network struggles against obvious attempts to shut them down.

Australian Flag with Fist-Held Syringe Superimposed

Australian Flag (by erjkprunczýk) with Fist-Held Syringe Superimposed

by Heidi Stevenson

The Australian Vaccination Network (AVN) has actively advocated for vaccination choice and provided information about vaccine risks for many years. Suddenly, the New South Wales Department of Fair Trading (DFT) has decided that their name is misleading and demanded that they change it. They have refused to state how it’s misleading and provided no advice about what change is required. They simply demand that the name be changed.

This may seem like a minor problem, but when an organization has existed for a long time, has a website based on their name, and trades under that name, being forced to change it is onerous. Nonetheless, AVN has done its best trying to cooperate, but they haven’t even been informed of how their name is supposed to be misleading! They have sent polite letters stating that they want to cooperate and asking the DFT to provide guidance. You can see three of them by clicking on these links: 27 December 201318 February 2013, and 6 March 2013.

They’ve gotten no response to their requests. So AVN requested a stay of the order, which is normally a fairly routine procedure. But their response was to declare that they must change their name immediately because it’s an emergency! AVN has existed since 1994—nearly 20 years—and it’s suddenly an emergency that they change their name?

After all, their actions against AVN clearly demonstrate that the Department of Fair Trading is most assuredly not living up to its name. It is, in fact, doing the oppositve—attempting to shut down a legitimate organization that is precisely what it claims, an organization that is a network of people in Australia on the subject of vaccination.

Obviously, there’s more to this than the desire to see their name changed. This is nothing less than part of an ongoing program designed to destroy the AVN. What reason could there be, other than to silence their voice?

So, AVN’s president, Greg Beattie, attended a hearing on 20 March 2013 regarding their request for a stay. Note that this now has moved into a legal matter requiring attorneys and their costs. Clearly, there’s no reason for doing this. After all, the AVN indicated willingness to cooperate, but they don’t know what needs to be done to satisfy the DFT—and the DFT has refused to advise them.

For this hearing, the DFT paid a group of people as expert witnesses. Why would they need expert witnesses for a simple extension hearing? And how much was paid to them? In any case, their expertise—whatever it is—seems not to have come into play, or if it did, it wasn’t clarified to AVN. Perhaps they should, instead, look inward and consider changing their name. I’ll even help them out: The Department of Speech Suppression would be ever so much more accurate!

AVN’s barrister laid out the reasons for granting a stay to allow the AVN staff time to consult with the membership. The government’s solicitor didn’t respond to what was said, merely stated that the public’s interest requires that AVN change it’s name now! Why, though, wasn’t explained.

To save money, both Beattie and AVN’s barrister appeared by telephone, since they are not located in New South Wales. DFT’s solicitor, though, in a show of pettiness, complained that it was an imposition, and the Member—Australian term for a judge—went along with it. Therefore, AVN’s barrister must show up in person, which means that AVN must cover the cost of flights and expenses.

Lest you have any doubts about DFT’s attitude towards AVN, the night before the hearing, AVN’s barrister was contacted by DFT’s legal representative. He treated AVN”s barrister extremely rudely and called AVN “fucking wackos”. They don’t like having their actions pointed out to the public, so deny AVN’s right to post the fact of this abominable behavior.

Attack on the Right to an Independent Viewpoint

AVN is clearly under attack. It isn’t because of any actual crime. It’s simply because they’re espousing a viewpoint that runs counter to the government’s. What’s under attack is the right to free speech. The point that needs to be understood is that this is not about whether vaccinations are good or bad. It’s about whether an organization or individual has the right to espouse a point of view that’s different from the government’s.

As it now stands, the government is acting as an enforcer of corporate interests. Big Pharma and Big Medicine want to promote and sell vaccines. AVN, apparently, is making headway against their profit machine … so the government is attacking AVN in the pettiest manner possible. There can be little doubt that the goal is to shut them down, to quiet their voice.

This is not the first attack on AVN. As reported earlier, a vicious attack on Meryl Dorey, AVN’s founder, was launched. She was subjected to vile pornographic messages and threatened over and over by phone. A distributed denial of service attack was launched against their website. Yet, the police and agencies that are supposed to protect people from such treatment failed to respond.

Last year, on the basis of two complaints, the Health Care Complaints Commission (HCCC) launched an investigation of AVN. They ordered AVN to include a statement on their site that states:

the Australian Vaccination Network’s purpose is to provide information against vaccination in order to balance what it believes is the substantial amount of pro-vaccination information available elsewhere;
the information should not be read as medical advice and;
the decision about whether or not to vaccinate should be made in consultation with a health care provider.

Obviously, only the medical monopoly is granted the right to make statements about health issues. It matters not if they’re right or wrong, the general public is not supposed to question them.

The HCCC also stripped their right to fund raise. AVN fought back and that right was returned to them.

Current Status

The AVN has won an extension until June to consult with members, but have been forced to place a consumer warning notice on their website reading:

Consumer Warning: NSW Fair Trading has directed Australian Vaccination Network to change its name because it regards the name to be misleading. The Australian Vaccination Network is challenging this Direction and the challenge is currently before the NSW Administrative Decisions Tribunal.

AVN was quite happy to do so. It clearly indicates to anyone who isn’t completely blinded to the corporate-owned government that freedom of speech is no longer considered a right. You can see it posted proudly at the top of every page on their site.

If you can possibly help AVN, please do. It’s clear that they’re in a battle for their existence, and equally clear that they’re also fighting for our right to hear the other side of the vaccine debate. Surely it’s obvious that this is everyone’s cause. Whether you agree with AVN or disagree vehemently, surely it’s obvious that they have the right to express their point of view. If the suppression doesn’t stop here, where will it stop?

You can contact the New South Wales Department of Fair Trading and tell them that their function is not defined as suppression of speech. It’s to provide a fair ground for everyone to trade. The right to free speech belongs to us all, not only those who agree with the government.

The phone number is (02) 9228 5276.

As AVN has stated, “You can act now—or you can wait for the knock on your door telling you your right to say no to drug-based therapies and medical vaccination has been taken away for good. The choice is yours.”

17 Examples of Admitted Vaccine Failure

Feb 23rd, 2013 | By | Category: Jeffry John Aufderheide, Top Storiesvaccine-effectiveness

Let’s face it.

As parents, we’re inundated with mixed messages about vaccines.

On one hand, doctors and mainstream media tell you how effective and safe vaccines are. On the other hand, you have parents like me who claim vaccines injured their children, or, in this case, that vaccines really “don’t work” as advertised.

What is often quickly forgotten is how often (and badly) vaccines fail. Ask yourself, “Why don’t these vaccine failures regularly make the news?”

If you can imagine in your mind’s eye, for a moment, the cash register “cha-chinging” while Big Pharma is pulling out a wad of cash, I think you may be getting close to the real answer. There’s big money in making sure the vaccine program is perceived as a success by you.

But this isn’t why you’re here.

Before I give you the 17 examples of how vaccines have failed, please investigate the United States vaccine schedule. Children are injected with 36 vaccines by the time they are 6 years of age.

number-vaccines

The United States has the most aggressive vaccine schedule in the world.

You’ll notice a common theme that when vaccines fail, the proposed solution is often more vaccines, even when the child has already received multiple doses to “protect” them.

As promised, here are examples of the children being injected with toxic and ineffective vaccines, which their parents trusted would protect their children from getting the disease.

Vaccine Failure #1 – Mumps Outbreak in Orthodox Jewish Communities in the United States (2010)

A large mumps outbreak occurred among highly vaccinated U.S. Orthodox Jewish communities during 2009 and 2010. Of the teenagers vaccinated,

  • 89% had previously received two doses of a mumps-containing vaccine
  • 8% had received one dose

Those infected who received a vaccine: 97%. [1]

 

Vaccine Failure #2 – Mumps Epidemic in Iowa (2006)

In March, 2006, a total of 219 mumps cases had been reported in Iowa – the largest epidemic of mumps in the United States since 1988.

Of the 219 cases reported in Iowa, the average age of infection was 21. Of the 133 patients investigated with a vaccine history,

  • 87 (65%) had received 2 doses
  • 19 (14%) had received 1 dose
  • 8 (6%) had no doses
  • 19 (14%) vaccine status could not be documented

Those infected who received a vaccine: 79% (at least). [2]

 

Vaccine Failure #3 – Mumps Outbreak at a Summer Camp in New York (2005)

On July 26, 2005, the New York State Department of Health identified 31 cases of mumps, possibly introduced by an unvaccinated camp counselor from the United Kingdom (UK). The vaccine coverage for the entire camp was 96%. Of the infected 31,

  • 16 (52%) had received 2 doses
  • 4 (13%) had received 1 dose
  • 9 (29%) had no doses
  • 2 (6%) vaccine status could not be documented

20 of the 31 people infected (65%) of the people infected were vaccinated.

Vaccine coverage for the camp: 96%. [3]

 

Vaccine Failure #4 – Mumps Outbreak in a Highly Vaccinated Population (1989)

From October 1988 to April 1989, an outbreak involving 269 cases of mumps occurred in Douglas County, Kansas. Of the 269 cases, 208 (77.3%) occurred among primary and secondary school students, of whom 203 (97.6%) had received a mumps vaccination. [4]

 

Vaccine Failure #5 – Two Fully Vaccinated Doctors Get Measles (2009)

A measles outbreak in 2009 exposed and infected two physicians, both of whom had been fully vaccinated with two doses of the MMR vaccine. These physicians were suspected of having been infected by treating patients diagnosed with measles.

Scoreboard: Measles 2 – Vaccinated Doctors 0. [5]

 

Vaccine Failure #6 – Major Measles Epidemic in Quebec Despite 99% Vaccine Coverage (1989)

The 1989 measles outbreak infecting 1,363 people in the province of Quebec was attempted to be explained away as occurring because of “incomplete vaccination coverage.”

However, upon further investigation, it was discovered the vaccination coverage among cases was at least 84.5%. Vaccination coverage for the total population was 99.0%.

Vaccine coverage for population: 99% [6]

 

Vaccine Failure #7–Outbreak of Measles Despite Appropriate Control Measures (1985)

In 1985, of 118 cases of measles which occurred on a Blackfeet reservation in Montana, 82% were vaccinated. Twenty-three of those cases occurred in the schools in Browning, Montana, where 98.7% of students were vaccinated. [7]

 

Vaccine Failure #8 – Measles Outbreak in a Fully Immunized Secondary-School Population (1985)

In 1985, an outbreak of measles occurred in a secondary school located in Corpus Christi, Texas. More than 99% had records of vaccination with live measles vaccine. The investigators concluded “that outbreaks of measles can occur in secondary schools, even when more than 99 percent of the students have been vaccinated and more than 95 percent are immune.

Vaccine coverage for school: 99%. [8]

 

Vaccine Failure #9 – Measles in an Immunized School-Aged Population in New Mexico (1984)

The story keeps repeating.

In 1984, 76 cases of measles were reported in Hobbs, New Mexico. Forty-seven cases (62%) occurred among students. The school reported that 98% of students were vaccinated against measles before the outbreak began.

Vaccine coverage for school: 98% [9]

 

Vaccine Failure #10 – Measles Outbreak Among Vaccinated High School Students in Illinois (1984)

In 1984, 21 cases of measles occurred in Sangamon County, Illinois.

  • 16 (76%) were vaccinated
  • 4 (19%) were unvaccinated preschool children
  • 1 (5%) vaccinated college student

All 411 students of the local high school were documented as having received the vaccination on or after their first birthday. Investigators remarked, “This outbreak demonstrates that transmission of measles can occur within a school population with a documented immunization level of 100%.

Vaccine coverage in school children contracting measles: 100% [10]

 

Vaccine Failure #11 – Analysis of Measles Epidemic; Possible Role of Vaccine Failures (1975)

In 1975, a measles epidemic occurred in schools in Greensville, Ontario. Out of the 47 cases of measles,

  • 26 (55.3%) had been vaccinated
  • 18 (18.3%) had not been vaccinated
  • 3 (6.4%) vaccine status unknown

Researchers concluded one vaccine isn’t enough to protect children. They recommended children be injected with an additional measles vaccine.

Cases of measles in vaccinated children: 55.3%. [11]

 

Vaccine Failure #12 – Unexpectedly Limited Durability of Immunity Following Acellular Pertussis Vaccination in Pre-Adolescents in a North American Outbreak (2012)

In 2012, doctors at Kaiser Permanente Medical Center identified 171 cases of pertussis – 132 in children. They noticed increased cases in children between the ages 8-12. They claim vaccine effectiveness was as follows:

  • For ages 2-7: 41% effective (?!?)
  • For ages 8-12: 24% effective (?!?)
  • For ages 13-18: 79% effective

Outside of using colorful adjectives such as garbage, worthless, or junk, the doctors hypothesized children need more vaccines to become “adequately protected.”

Vaccine effectiveness for ages 8-12: 24%. [12]

 

Vaccine Failure #13 – Clinical Presentation of Pertussis in Fully Immunized Children in Lithuania (2001)

In 2001, Lithuania’s vaccine coverage was 94.6% as a country. From May to December of that year, 53 children showed a serological confirmation of pertussis. Of the 53 children,

  • 32 (60.4%) were fully vaccinated
  • 21 (39.6%) were partially vaccinated or unvaccinated

Researchers conveniently grouped both partially vaccinated and unvaccinated children together. Twenty-eight of 32 fully vaccinated children (87.5%) had also received antibiotics.

Vaccinated children (who received at least three DTP vaccine doses) represented 43.2% of all pertussis cases diagnosed in 2001.

Vaccine coverage for Lithuania: 94.6%. [13]

 

Vaccine Failure #14 – Pertussis Infection in Fully Vaccinated Children in Day Care Centers (2000)

Many health professionals are adamant that vaccines protect against infection. Evidence from a field investigation in Israel challenges this belief.

In 2000, a child died suspected of having pertussis. The baby received the first dose of DTP at two months of age – all family members were completely vaccinated with four doses of DTP.

The day care centers that two siblings had attended during the child’s illness were investigated. All the children in the day care had been vaccinated in infancy with four doses of diphtheria-tetanus toxoid pertussis (DTP) vaccine, and a booster dose at 12 months of age.

Five fully vaccinated children were found to be colonized with Bordetella pertussis.

At the conclusion of the investigation, researchers stressed the following information:

Vaccinated adolescents and adults may serve as reservoirs for silent infection and become potential transmitters to unprotected infants. The whole-cell vaccine for pertussis is protective only against clinical disease, not against infection. Therefore, even young, recently vaccinated children may serve as reservoirs and potential transmitters of infection.

They re-emphasized again, “Our results indicate that children ages 5-6 years and possibly younger, ages 2-3 years, play a role as silent reservoirs in the transmission of pertussis in the community.

Vaccine coverage in daycare: 100% [14]

Vaccine Failure #15 – Pertussis Outbreak in Vermont (1996)

In 1996, over 280 cases of pertussis cases were identified in Vermont. Here is the breakdown of the age groups of those infected:

  • 12 (4%) were aged less than 1 year
  • 32 (11%) were 1-4 years
  • 42 (15%) were 5-9 years
  • 129 (46%) were 10-19 years
  • 65 (23%) were greater than or equal to 20 years

How many of these 215 children were vaccinated? According to the report, of the children who had a known vaccine status,

  • 5 children aged 7-47 months were partially vaccinated
  • 14 children aged 7-47 months were vaccinated with 3 doses
  • 49 children aged 7-18 years were partially vaccinated
  • 106 children aged 7-18 years were fully vaccinated

Disturbingly, 174 children were vaccinated and over half (61%) of the school children were considered “fully vaccinated!” It’s also important to keep in mind that in 1996, 97% of children aged 19-35 months in Vermont had received three or more doses of DT or DTP vaccine.

Complete failure in vaccinated children: at least 80.9% [15]

 

Vaccine Failure #16 – Outbreak of Varicella at a Day Care Center Despite Vaccination (2012)

Sometimes instead of saying a vaccine is a complete failure, a term such as “breakthrough varicella” is used to describe how children get the disease for which they were vaccinated.

In December of 2012, an outbreak occurred in a private day care center in a small community near Concord, New Hampshire. There were a total of 25 cases of varicella reported in children.

  • 17 (68%) were vaccinated
  • 8 (32%) were unvaccinated – two of these children were vaccinated in late December and classified as “unvaccinated”

The investigators lamented that the vaccine was 44% effective, saying, “The reasons for the poor performance of the vaccine are not apparent…the findings in this investigation raise concern that the current vaccination strategy may not protect all children adequately.

Vaccine coverage: 73.1% [16]

 

Vaccine Failure #17 – An Outbreak of Chickenpox in Elementary School Children with Two-Dose Varicella Vaccine Recipients (2006)

When it is apparent one vaccine isn’t working, the answer is almost always more vaccines… ever notice?

In June 2006, a second dose of the chickenpox (varicella) vaccine was recommended for school entry. Shortly after school had begun, the Arkansas Department of Health was notified of a varicella outbreak in students.

Vaccination information was available for 871 (99%) of the 880 children. Ninety-seven percent of the children had been vaccinated for varicella! In this outbreak, 84 cases were reported.

Vaccine coverage: 97%. [17]

 

Conclusion

As you can see from the above examples, vaccines fail and do so often. Trust me, there are many more examples I didn’t cover here.

Here’s a tip for you if you want to look for more information. Open your browser right now. Go to Google.com and do a search for the terms “previously immunized for (x)” or “breakthrough (x) in school.” X, of course, represents a “vaccine preventable” disease such as pertussis, measles, varicella, etc., – you get the point.

As a parent, you trust doctors to provide you with accurate information. When doctors say vaccines work and they are effective, from whom are they getting their information?

Maybe even more importantly, why aren’t the vaccine failures covered by mainstream media to inform you? The likely answer is the organizations who really need protection from the truth are the members of Big Pharma – and I don’t think there is a vaccine for that (although they may try to create one).

If you find other examples, please post them below (with the link to PubMed) for other parents to read.

 

References

 

  1. http://www.nejm.org/doi/full/10.1056/NEJMoa1202865
  2. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm55d330a1.htm
  3. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5507a2.htm
  4. http://www.ncbi.nlm.nih.gov/pubmed/1861205
  5. http://jid.oxfordjournals.org/content/204/suppl_1/S559.full.pdf+html
  6. http://www.ncbi.nlm.nih.gov/pubmed/1884314
  7. http://www.ncbi.nlm.nih.gov/pubmed?term=3618578
  8. http://www.nejm.org/doi/full/10.1056/NEJM198703263161303
  9. http://www.cdc.gov/mmwr/preview/mmwrhtml/00000476.htm
  10. http://www.cdc.gov/mmwr/preview/mmwrhtml/00000359.htm
  11. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1956577/
  12. http://cid.oxfordjournals.org/content/early/2012/03/13/cid.cis287
  13. http://www.ncbi.nlm.nih.gov/pubmed/15918913
  14. http://wwwnc.cdc.gov/eid/article/6/5/00-0512_article.htm
  15. http://www.cdc.gov/mmwr/preview/mmwrhtml/00049244.htm
  16. http://www.nejm.org/doi/full/10.1056/NEJMoa021662
  17. http://www.ncbi.nlm.nih.gov/pubmed/19593254

Treating cancer with dissimilar disease

By Dr. Guillermo Zamora, a surgeon UAG, Homeopath (Dhom. Med) by the Institute for Homoeopathic Medicine.

Herpes

For those who question the strength of the inductive method of reasoning applied to medicine proposed by Hahnemann, put as an example if not its antithesis, if it is unduly partial observation of an event, the report that for several days been going on for the journal Public Library of Science Pathogens [1] and has been published in various journals, conferences, websites, and magazines [2].

This report mentions that a genetically modified virus ["oncolytic" herpes simplex virus (HSV)] has been created, and is able to block the spread of ovarian cancer and breast cancer in mice. It seems important to mention that different sources of conventional medicine, have been saying this for several years.

Chief Scientist, Professor Gabriella Campadelli-Fiume, University of Bologna in Italy, said: “Many laboratories worldwide are using more specific viruses as weapons against cancer cells, called oncolytic viruses.”

“Safety concerns prevailed so far, and all oncolytic herpes virus now in clinical trials are weakened viruses, effective only against a fraction of tumors.”

“We were the first to obtain a reprogrammed herpes virus to enter positive tumor cells, unable to infect other cells, but retains the same ability to kill in order that the wild-type HSV.”

According to Dr. Kevin Harrington, Institute of Cancer Research in London, who is leading oncolytic virotherapy studies [3], has been obtained “success” in up to 93% of cases in which the virus (and other viruses such as reovirus and adenovirus) has been modified to not infect healthy tissue (?) and according to the studies could become successful treatment in the fight against head and neck cancer.

With FDA approval, studies (including multicenter) are carried out in different phases using intratumoral injection in order to evaluate the response of colony stimulating factor-granulocyte macrophage [JS1/34.5-/47-/granulocyte -macrophage colony-stimulating factor (GM-CSF)] in different types of advanced cancer. Studies may include combinations of chemotherapy with cyclophosphamide, docetaxel, 3-AP Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone), radiation therapy, or combined chemoradiation in which studies show is “synergy” between all therapies. Side effects such as anemia, nausea, and fatigue are often reported, and neutropenia. One speaks of proviral states as vascular endothelial growth factor (vascular endothelial growth factor or VEGF) during which the reovirus can replicate oncolytic administered systemically in the endothelium, thereby inducing immune-mediated vascular collapse with significant antitumor properties.

Many studies show how are you amazing results with proven results in the treatment of certain cancers. However, the long term effects of drug-biological treatments, dependence and the tendency to acquire another disease state or immune weakness, are some maxims that should worry us. No medical intervention or treatment should be given without a long period of experimentation and testing (*). A Hahnemann It took eight years before he started dealing with Homoeopathy. There are many books, documents and writings and research experiments on the reactions, similarities, and results before he carefully follow each step with your therapy.

(*) This warning applies also for studies with the name “Homoeopathy” is conducted for cancer treatment (for example the protocol Banerji Homeopathic Research Foundation), especially when real has not been practiced homeopathy for decades for most of the “homeopathic”.

Something that has not been taken into account is that one thing is the infectious agent with whom you work for any purpose, and one is the reaction-disease so mild, moderate or severe body generates all contacts that agent. Any modified agent however, can not be discriminative enough not to cause a reaction in the center of the life force (wherever it is), as we saw with the immediate side effects reported as anemia, nausea, fatigue and neutropenia.

The experimental study is developed with the herpes virus, derived from observation (as I said at the beginning, unduly partial) that people with cancer and at the same time acquire or come into contact with people infected with the herpes virus appear stop development of its initial cancerous state, and even reverse it [4]. (I translate an extract of the reference number 4 on the history of oncolytic therapy, for the convenience of our readers)

“It seems that the use of viruses in cancer treatment was not the result of some insightful theory of alternative therapy, but rather only derived from the observation that, occasionally, cancer patients who contracted an infectious disease had brief periods clinical remission. “

So, we put a lot of attention. We must not lose the entire complex under which certain conditions are favoring the experimental subjects, who were either inmunosuprime (even when it is intended to search a localized immune response), or causes them to weaken their disease through chemo and / or radiation while trying to “attack” the tumor with the modified virus. This means that protocols require that artificially weaken, suppress or maintain and produce a susceptibility to opportunistic infectious miasm widely known, but enough to make it amended as yet unknown. With this, it will be predicted drug dependence or ultimately death because desarmonizado balance that sustains life. We will see later why.

This herpes and cancer research leads me to remember what Hahnemann had observed about through simple inductance and I would have liked to have been taken into account by the researchers (or perhaps if they knew about it?). This would comment that we do not object to people using their preferred therapy or oppose personal opinions. What we would like is that these observations are considered under Baconian establish a new era in science as applied to medicine.

I can not leave out, mention the fact that prior experimentation on animals has serious drawbacks, including:

  • Animals can not express subjective symptoms produced during the experiment.
  • Infective agents (read infecting agent perspective Hahnemanniana) act differently in each species.
  • Humans and animals react differently to these infectious agents.
  • There are substances in animals may be harmless, while for men can be highly toxic and vice versa.
  • Man or animal (host) can act as a reservoir and in turn so individualized in each body of each species cause changes (mutations) to infective agents making them more potent complexes, reactivándolos (eg after attenuated) or increasing their virulence ( **).

(**) Vaccines may also be applied to the same vial containing three viruses or vaccines contaminated with unknown viruses. [5, 6.7 to cite some references, but there is enough hemerography about]

As I mentioned before and want to accept it or not researchers oncolytic viral therapy (they did not know, did not understand, did not care or did purposely. No) [4], for almost 200 years, Hahnemann had already observed in As regards to the reaction-disease, three circumstances where two dissimilar diseases coexist in the body of a human being, I quote two of those three circumstances with some of his remarks and references:

Aphorism § 38, Organon, 6th. edition

“II. – New to dissimilar disease is the strongest. – In this case the disease under which the patient lived primitively, being the weakest, will be arrested and suspended by the emergence of stronger, until it cross its course or be cured, then the old reappears uncured.

  • “As noted Tulpius 72 two children suffering from some form of epilepsy, were free of attacks after being infested with ringworm (instep), but as soon as the eruption of epilepsy head disappeared again as before. (72 Obs., lib. i, obs. 8)

 

  • Scabies, as noted Schopf 73 submitted scurvy disappeared, but after it healed, that reappeared. (72 Obs., lib. i, obs. 8)

 

  • So also remained stationary pulmonary tuberculosis patient being attacked by a violent typhus, but continued their march after typhus ran its course. 74   (74 Chevalier, in Hufeland’s Neuesten Annalen der Französiche, Heiljunde, ii, p. 192)

 

  • When the measles and smallpox together dominate, and both attack the same child, measles-existing, generally is contained by smallpox appeared later; measles does not end until it ends its course smallpox, but not uncommon it happens that the smallpox infection is suspended for four days by the supervening of measles, after which scaling complete your smallpox, as observed by Manget. 76 (76 In Edimb. Med Comment., Pt. I, I)

 

  • So with all dissimilar diseases, the strongest stops development of the weakest (if not complicated which is rare in acute diseases), but never a cure to the other. “(My emphasis)

 

The aphorism § 40, 6th Organon. Editing refers to a combined response (or response miasmatic disease combined mutant)

“III. – The new disease, after he had worked a long time in the body, finally joins that is unlike the former, and forms with it a complex disease, so that each occupies a special location in the body, ie organs peculiarly adapted to it and only that particular location belongs, while leaving the remaining organs other disease that is unlike … For two dissimilar diseases can not be destroyed, can not be cured to one another … not However, there have also been major epidemics of this kind, in which two dissimilar acute and, in rare cases, have occurred simultaneously in one and the same body, and combined, as it were, for a short time with each other … then, though not completely incurable, but can be transformed into health with very great difficulty. “

  • “Rainey 86 witnessed the simultaneous occurrence of measles and smallpox in two girls. (86 Edinb. Med Comment, iii, p. 480)
  • J. Maurice 87 throughout its practice observed only two cases of this kind. (87 in Phys Med and Journ., 1,805)
  • Similar cases are found in the works of Ettmüller 88 and in the writings of some others. (88 Opera, ii, pi, chap. 10)
  • Lencker 89 vaccine was go full term together with measles and purple. (89 Hufeland’s Journal, X v ii) “

 

This latter circumstance applies for malnourished patients, and / or with certain addictions, and / or debilitating conditions, and / or in immunosuppressed patients, etc. A clear example of this would be all diseases “new” appearance as acquired immunodeficiency syndrome (AIDS), in which you can combine various diseases caused by two or more types of the herpes family (***) and microorganisms and other viral, bacterial, fungal, etc..

(***) In the last 100 years have discovered 8 different types of herpes.

1.-TYPE herpes simplex virus I.

2.-Herpes Simplex Virus Type II

3.-varicella-zoster virus.

4.-Epstein-Barr virus.

5.-CITAMEGALOVIRUS.

6.-herpesvirus-6-6-B AY. (HHV-6)

7.-herpesvirus 7 (HHV-7)

8.-human herpesvirus 8 (Kaposi’s sarcoma)

If we reflect the foregoing, we find that Hahnemann makes complete observations (and NO partial), deep and detailed the circumstances between two dissimilar diseases coexist, including the aftermath of the same, so we can see that the inductance in science, observe the experienced (even from the same accident or toxicity), helps predict the outcome of an event. Take into account the principles established by Hahnemann in the Organon for experimentation and the coexistence of two dissimilar diseases is not a minor thing. Accept and understand our limitations, our achievements, and the consequences of such applications in medicine is vital to our future and wellbeing.

References

[1] http://www.plospathogens.org/

[2] Huffingtonpost, Herpes Virus Could Be Key To Breast And Ovarian Cancer Treatment, The Huffington Post UK | Posted: 31/01/2013 22:16 GMT

GM virus blocks spread of cancer, Press Association – Thu, Jan 31, 2013, yahoo news.

Herpes virus, “new weapon” against cancer Join BBC Science, August 2, 2010 – 13:39 GMT

The herpes virus shows promise in treating breast cancer, Isaude, Science and Technology, published on 26/10/2011 at 13h58: 00

HERPES VIRUS SHOWS PROMISE IN TREATING EARLY TRIPLE-NEGATIVE BREAST CANCER Oncolytic viral therapy shows great potential for treating an aggressive form of breast cancer, News from the Clinical Congress, Yuman Fong, MD, FACS Sepideh Gholami, MD, Monday, October 24, 1:00 pm

[3] Donnelly, OG., Errington-Mais, F., Prestwich, R., Harrington, K., Pandha, H., Vile, R. & Melcher, AA. (2012) Recent Clinical Experience with oncolytic Viruses Current Pharmaceutical Biotechnology, Vol.13 (9), pp.1834-1841, ISSN: 1389-2010.

Adair, RA., Roulstone, V., Scott, KJ., Morgan, R., Nuovo, GJ., Fuller, M., Beirne, D., West, EJ., Jennings, VA., Rose, A., et al. (2012) Cell Carriage, Delivery, and Selective Replication of an oncolytic virus in Tumor in Patients Science Translational Medicine, Vol.4 (138), ISSN: 1946-6234.

Karapanagiotou, MS., Roulstone, V., Twigger, K., Ball, M., Tanay, M., Nutting, C., Newbold, K., Gore, ME., Larkin, J., Syrigos, KN., et al. (2012) Phase I / II trial of carboplatin and paclitaxel chemotherapy in combination with intravenous oncolytic reovirus in patients with Advanced Malignancies. Clin Cancer Res, Vol.18 (7), pp.2080-2089, ISSN: 1078-0432 .

Simpson, GR., Horvath, A., Annels, NE., Pencavel, T., Metcalf, S., Seth, R., Peschard, P., Price, T., Coffin, RS., Mostafid, H., et al. (2012) Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for bladder cancer Surface British Journal of Cancer, Vol.106 (3), pp.496-507, ISSN: 0007-0920 .

Kottke, T., Chester, J., Ilett, E., Thompson, J., Diaz, R., Coffey, M. Selby, P., Nuovo, G., Pulido, J., Mukhopadhyay, D., et al. (2011) Precise Scheduling of Chemotherapy Primes VEGF-producing Tumors for Successful Systemic oncolytic virotherapy MOL THER, Vol.19 (10), pp.1802-1812, ISSN: 1525-0016.

Heinemann, L., Simpson, GR., Boxall, A., Kottke, T., Relph, KL., Vile, R., Melcher, A., Prestwich, R., Harrington, KJ., Morgan, R., et al. (2011) Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer BMC CANCER, Vol.11 ISSN: 1471-2407.

Touchefeu, Y., Vassaux, G. & Harrington, KJ. (2011) oncolytic viruses in radiation oncology Radiother Oncol, vol.99 (3), pp.262-270, ISSN: 0167-8140.

Ilett, EJ., Barcena, M., Errington-Mais, F., Griffin, S., Harrington, KJ., Pandha, HS., Coffey, M., Selby, PJ., Limpens, RWAL., Mommaas, M . et al. (2011) Internalization of oncolytic Reovirus by Human Dendritic Cell Carriers from the Virus Neutralization Protects Clin Cancer Res, Vol.17 (9), pp.2767-2776, ISSN: 1078-0432.

Willmon, C., Diaz, RM., Wongthida, P., Galivo, F., Kottke, T., Thompson, J., Albelda, S., Harrington, K., Melcher, A. & Vile, R. (2011) Vesicular Stomatitis Virus-induced Suppressor Cells Immune Antagonism Between Intratumoral oncolytic Generate Virus and Cyclophosphamide Mol Ther, Vol.19 (1), pp.140-149, ISSN: 1525-0016.

Senzer, NN., Kaufman, HL., Amatruda, T., Nemunaitis, M., Reid, T., Daniels, G., Gonzalez, R., Glaspy, J., Whitman, E., Harrington, K., et al. (2009) Phase II Clinical Trial of a Granulocyte-macrophage colony-stimulating factor-Encoding, Second-Generation oncolytic herpesvirus in unresectable Patients With Metastatic Melanoma J CLIN ONCOL, Vol.27 (34), pp.5763-5771, ISSN: 0732-183x.

Harrington, KJ. (2010) Topical treatment for oral Cancers Winners and Losers and oncolytic adenoviruses: who should be down in the mouth? GENE THER, Vol.17 (12), pp.1421-1422, ISSN: 0969-7128.

Harrington, KJ., Hingorani, M., Tanay, MA., Hickey, J., Bhide, SA., Clarke, PM., Renouf, LC., Thway, K., Sibtain, A., McNeish, IA., et al. (2010) Phase I / II Study of oncolytic HSVGM-CSF in Combination with Cisplatin in Untreated Radiotherapy and Stage III / IV Squamous Cell Cancer of the Head and Neck Clin Cancer Res, Vol.16 (15), pp.4005 -4015, ISSN: 1078-0432.

Merron, A., Baril, P., Martin-Duque, P., de la Vieja, A., Tran, L., Briat, A., Harrington, KJ., McNeish, IA. & Vassaux, G. (2010 ) Assessment of the Na / I symporter gene as a reporter to visualize oncolytic adenovirus propagation in peritoneal Tumours Eur J Nucl Med MOL I, Vol.37 (7), pp.1377-1385, ISSN: 1619-7070.

Kottke, T., Hall, G., Pulido, J., Diaz, RM., Thompson, J., Chong, H., Selby, P., Coffey, M., Pandha, H., Chester, J., et al. (2010) Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of tumors in mice Established J CLIN INVEST, Vol.120 (5), pp.1551-1560, ISSN: 0021-9738.

Harrington, KJ., Vile, RG., Melcher, A., Chester, J. & Pandha, HS. (2010) Clinical trials with oncolytic reovirus: moving beyond phase I into combinations with standard therapeutics. Cytokine Growth Factor Rev, Vol.21 (2-3), pp.91-98.

Senzer, NN., Kaufman, HL., Amatruda, T., Nemunaitis, M., Reid, T., Daniels, G., Gonzalez, R., Glaspy, J., Whitman, E., Harrington, K., et al. (2009) Phase II Clinical Trial of a Granulocyte-macrophage colony-stimulating factor-Encoding, Second-Generation oncolytic herpesvirus in unresectable Patients With Metastatic Melanoma J CLIN ONCOL, Vol.27 (34), pp.5763-5771, ISSN: 0732-183x.

Willmon, C., Harrington, K. Kottke, T., Prestwich, R. Melcher, A. & Vile, R. (2009) Cell Carriers for oncolytic Viruses: Fed Ex for Cancer Therapy MOL THER, Vol.17 (10), pp.1667-1676, ISSN: 1525-0016.

Prestwich, RJ., Errington, F., Steele, LP., Ilett, EJ., Morgan, RSM., Harrington, KJ., Pandha, HS., Selby, PJ., Vile, RG. & Melcher, AA. (2009) Reciprocal Human Dendritic Cell-Induced Natural Killer Cell Interactions Following Antitumor Activity Tumor Cell Reovirus Infection by oncolytic J Immunol, Vol.183 (7), pp.4312-4321, ISSN: 0022-1767.

Pandha, HS., Heinemann, L., Simpson, GR., Melcher, A., Prestwich, R., Errington, F., Coffey, M., Harrington, KJ. & Morgan, R. (2009) Synergistic Effects of oncolytic Reovirus and Cisplatin Chemotherapy in Murine Malignant Melanoma CLIN CANCER RES, Vol.15 (19), pp.6158-6166, ISSN: 1078-0432.

Prestwich, RJ., Errington, F., Diaz, RM., Pandha, HS., Harrington, KJ., Melcher, AA. & Vile, RG. (2009) The Case of oncolytic Viruses Versus the Immune System: Waiting on the Judgment of Solomon HUM GENE THER, Vol.20 (10), pp.1119-1132, ISSN: 1043-0342.

Prestwich, RJ., Ilett, EJ., Errington, F., Diaz, RM., Steele, LP., Kottke, T., Thompson, J., Galivo, F., Harrington, KJ., Pandha, HS., et al. (2009) Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Replication Oncolysis and CLIN CANCER RES, Vol.15 (13), pp.4374-4381, ISSN: 1078-0432.

Pandha, H., Melcher, A., Harrington, K. & Vile, R. (2009) oncolytic Viruses: Time to Compare, Contrast, and Combine? MOL THER, Vol.17 (6), pp.934-935, ISSN: 1525-0016.

Ilett, EJ., Prestwich, RJ., Kottke, T., Errington, F., Thompson, JM., Harrington, KJ., Pandha, HS., Coffey, M., Selby, PJ., Vile, RG., et al. (2009) Dendritic cells and T cells deliver Tumour killing oncolytic DESPITE reovirus for pre-existing anti-viral immunity Gene Ther, Vol.16 (5), pp.689-699, ISSN: 0969-7128.

Kottke, T., Thompson, J., Diaz, RM., Pulido, J., Willmon, C., Coffey, M., Selby, P., Melcher, A., Harrington, K. & Vile, RG. (2009) Improved Systemic Delivery of Established Tumors to Reovirus oncolytic Using Preconditioning with Cyclophosphamide-Mediated Treg Modulation and Interleukin-2 Clin Cancer Res, Vol.15 (2), pp.561-569, ISSN: 1078 – 0432.

Prestwich, RJ., Errington, F., Ilett, EJ., Morgan, RSM., Scott, KJ., Kottke, T., Thompson, J., Morrison, EE., Harrington, KJ., Pandha, HS., et al. (2008) Tumor Infection by oncolytic Reovirus Primes Adaptive Antitumor Immunity CLIN CANCER RES, Vol.14 (22), pp.7358-7366, ISSN: 1078-0432.

Prestwich, RJ., Harrington, KJ., Pandha, HS., Vile, RG., Melcher, AA. & Errington, F. (2008) oncolytic viruses: a novel form of immunotherapy EXPERT ANTICANC REV, Vol.8 (10), pp.1581-1588, ISSN: 1473-7140.

Harrington, KJ., Melcher, A., Vassaux, G., Pandha, HS. & Vile, RG. (2008) Exploiting Synergies Between radiation and oncolytic viruses. Curr Opin Mol Ther, Vol.10 (4), pp.362-370, ISSN: 1464-8431.

Prestwich, RJ., Harrington, KJ., Vile, RG. & Melcher, AA. (2008) immunotherapeutic potential of oncolytic virotherapy LANCET ONCOL, Vol.9 (7), pp.610-612, ISSN: 1470-2045.

Kottke, T., Galivo, F., Wongthida, P., Diaz, RM., Thompson, J., Jevremovic, D., Barber, GN., Hall, G., Chester, J., Selby, P., et al. (2008) Treg depletion-enhanced IL-2 therapy of treatment Facilitates Established tumors delivered systemically using oncolytic virus Mol Ther, Vol.16 (7), pp.1217-1226, ISSN: 1525-0016.

White, CL., Twigger, KR., Vidal, L., De Bono, JS., Coffey, M., Heinemann, L., Morgan, R., Merrick, A., Errington, F., Vile, RG. , et al. (2008) Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial. Gene Ther, Vol.15 (12), pp.911-920.

Qiao, J., Kottke, T., Willmon, C., Galivo, F., Wongthida, P., Diaz, RM., Thompson, J., Ryno, P., Barber, GN., Chester, J., et al. (2008) Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, immunotherapy and virotherapy oncolytic Nat Med, Vol.14 (1), pp.37-44, ISSN: 1078-8956.

Hu, JC., Coffin, RS., Davis, CJ., Graham, NJ., Groves, N., Guest, PJ., Harrington, KJ., James, ND., Love, CA., McNeish, I., et al. (2006) A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res, Vol.12 (22), pp.6737-6747, ISSN: 1078-0432.

[4] NATURE, Molecular Therapy (2007) 15 4, 651-659 doi: 10.10, “History of oncolytic Viruses: Genesis to Genetic Engineering”, Elizabeth Kelly and Stephen J Russell:

“It Appears That the use of viruses in the treatment of cancer was not the result of some perspicacious theory of an alternative therapy but Rather stemmed from the observation just That, occasionally, Contracted cancer patients who went into an infectious disease brief periods of clinical remission . “

[5] Modulation of immune responses during canine distemper virus infection: implications for therapeutic and vaccine development, Céspedes PF *, P Cruz, CO Navarro, Faculty of Veterinary and Animal Sciences, Laboratory of Animal Virology, University of Chile , Santiago, Chile. Arch Med Vet 42, 15-28 (2010):

“This last statement is based on evidence of the ability of the attenuated vaccine virus to revert to virulence so fleeting and cause lethal encephalitis in dogs following immunization and, similarly, a multisystem box of 90-100% morbidity and lethality in ferrets blacklegged (Mustela putorius furo) (Summers and Appel 1994, von Messling et al 2003). “

[6] Reverse Genetics for Live Attenuated Virus Vaccine Development Kun Yao, * and Zaishi Wang

“… An attenuated virus can still replicate in the Vaccinated Individuals, Therefore, the virus has the potential to revert to virulent phenotypes. Moreover, some of live vaccines can be Transmitted from the person to non immunized Vaccinated Individuals … “

“These are particularly important safety Concerns for Certain human RNA human parainfluenza viruses Such as virus (PIV), respiratory syncytial virus (RSV) and HIV, since viruses These RNA, RNA-dependent RNA Whose polymerases do not have a proofreading function and a high Could Occur During mutation rate virus replication. “

[7] Altered Virulence of Vaccine Strains of Measles Virus after Prolonged Replication in Human Tissue, Alexandra Valsamakis et al, J Virol. October 1999, 73 (10): 8791-8797.

The ineffectiveness and unintended consequences of measles vaccination

by Dr Viera Scheibner (PhD)
International Medical Counsel on Vaccination

Measles vaccine introduction

Measles vaccination in the US and many other countries started in the early 1960s, at the time when measles was naturally abating and was heading for the 18 year low. That’s why the vaccine seemingly lowered the incidence; however, this was only coincidental with the natural dynamics of measles.

us measles 1024x637 Outbreaks of Measles in Vaccinated Children Intensifying

Image from healthsentinel.com - Click image to enlarge.

As one of many examples involving all infectious diseases of childhood against which vaccines have been developed, ever since any measles vaccines have been introduced and used in mass proportions, reports of outbreaks and epidemics of measles in even 100% vaccinated populations started filling pages in medical journals.

Reports of serious reactions including deaths also appeared with increasing frequency. They are the subject of a separate essay.

Atypical measles – a new phenomenon only in the vaccinated

It is less well known to the general public that vaccinated children started developing an especially vicious form of measles, due to the altered host immune response caused by the deleterious effect of the measles vaccines. It resisted all orthodox treatment and carried a high mortality rate.

It has become known as atypical measles. (AMS)

Rauh and Schmidt (1965) described nine cases of AMS which occurred in 1963 during a measles epidemic in Cincinnati. The authors followed 386 children who had received three doses of killed measles virus vaccine in 1961. Of these 386 children, 125 had been exposed to measles and 54 developed it [i.e. measles].

The new, atypical measles, occurring in the vaccinated was characterised by high fever, unusual rash and pneumonia, often with history of vaccination with killed measles vaccine.

Rauh and Schmidt (1965) concluded that, “It is obvious that three injections of killed vaccine had not protected a large percentage of children against measles when exposed within a period of two-and-a-half years after immunization”.

Fulginiti (1967) also described the occurrence of atypical measles in ten children who had received inactivated (killed) measles virus vaccine five to six years previously.

Nichols (1979) wrote that atypical measles is generally thought to be a hypersensitivity response to natural measles infection in individuals who have previously received killed measles vaccine, although several investigators have reported AMS-like illness in children who had been vaccinated only with live measles vaccine.

He wrote that during a measles epidemic in 1974-1975 in Northern California, a number of physicians reported laboratory-confirmed measles in patients who had signs and symptoms, compatible with AMS…”We developed case criteria on the basis of serology and rash distribution and morphology. In typical measles a maculopapular rash occurs first at the hairline, progresses caudally, is concentrated on the face and trunk, and is often accompanied by Koplik’s spots. In AMS the rash Is morphologically a mixture of maculopapular, petechial, vesicular, and urticarial components. It usually begins and is concentrated primarily on the extremities, progresses cephalad, and is not accompanied by Koplik’s spots. Cases were classified as AMS if patients had 1) a rash with the distribution and morphology characteristic of AMS, and 2) a fourfold or greater rise in titer of complement-fixing measles antibody or a convalescent titer of 256”.

Continuing measles outbreaks signal increasing incidence comparable with the prevaccine era.

In the meantime, outbreaks of measles in vaccinated children have continued and intensified to this day. Contemporary observations of the ineffectiveness of vaccination indicate to me that the incidence of measles has increased and has not continued decreasing as it did for some 100 years before any type of measles vaccination was introduced.

Conrad et al. (1971) published about the dynamics of measles in the US in the last four years and conceded that measles was on the increase and that “eradication, if possible, now seems far in the future”.

Barratta et al. (1970) investigated an outbreak in Florida from December 1968 to February 1969 and found little difference in the incidence of measles in vaccinated and unvaccinated children.

Right through the 1980s, measles outbreaks in fully vaccinated children have continued all over the US and all other countries with high vaccination rates all over the world.

Robertson et al. (1992) wrote that in 1985 and 1986. 152 measles outbreaks in US school-age children occurred among persons who had previously received measles vaccine. “Every 2-3 years, there is an upsurge of measles irrespective of vaccination compliance”.

To cap it all: the largely unvaccinated Amish (they claim religious exemption) had not reported a single case of measles between 1970 and December 1987, for 18 years (Sutter et al. 1991). It is quite likely that a similar situation would have applied to outside communities without any vaccination and that measles vaccination had actually kept measles alive and kicking. According to Hedrich (1933), there is a variety of dynamics of measles occurrence, from 2-3 years to up to 18 years, as later also witnessed by the unvaccinated Amish.

Unfounded optimism for measles eradication in the US by 1 October 1982

Despite the obvious lack of success with measles vaccination, in October 1978, the Secretary of the Department of Health, Joseph A Califano Jr. announced, “We are launching an effort that seeks to free the United States from measles by 1 October 1982″.

Predictably, this unrealistic plan fell flatly on its face: after 1982 the US was hit repeatedly by major and even more sustained epidemics of measles, mostly in fully vaccinated populations. First, the blame was laid upon the “ineffective, formalin-inactivated (‘killed’) measles vaccine, administered to hundreds of thousands of children from 1963 to 1967″. However, outbreaks and epidemics of measles continued occurring even when this first vaccine was replaced with two doses of ‘live’ measles virus vaccines and the age of administration was changed.

These warnings have not been heeded. As the Swiss doctors wrote (Albonico et al. 1990), “we have lost the common sense and wisdom that used to prevail in the approach to childhood diseases. Too often, instead of reinforcing the organism’s defences, fever and symptoms are relentlessly suppressed. This is not always without consequences”.

Destruction of transplacentally-transmitted immunity by vaccination

Many researchers warned straight after the introduction of measles vaccine in the US that the generations of children born to mothers who were vaccinated in childhood will be born with poor or no transplacentally-transmitted immunity and will contract measles and other diseases too early in life.

Lennon and Black (1986) demonstrated that “haemaglutinin-inhibiting and neutralizing antibody titers are lower in women young enough to have been immunized by vaccination than older women”. The same applied to whooping cough. It explains why so many babies before vaccination age develop these diseases, and most particularly the much publicised whooping cough.

Read the Full Article Here: http://www.vaccinationcouncil.org/2013/01/18/the-ineffectiveness-of-measles-vaccines-and-other-unintended-consequences-by-dr-viera-scheibner-phd

About the author

Dr Viera Scheibner is Principal Research Scientist (Retired) with a doctorate in Natural Sciences from Comenius University in Bratislava. After an eminent scientific career in micropalaeontology during which she published 3 books and some 90 scientific papers in refereed scientific journals in Australia and overseas, she studied babies’ breathing patterns with the Cotwatch breathing monitor developed by her late husband Leif Karlsson in the mid 1980s. Babies had alarms after vaccination, indicating stress. This introduced her to the subject of vaccination. She then started systematically studying orthodox medical papers dealing with vaccination issues. To this day she has collected and studied more than 100000 pages of medical papers.

Despite such extensive research of orthodox medical papers published on vaccines over the past 100 years, she established that there is no scientific evidence that these injections of highly noxious substances prevent diseases, quite to the contrary, that they increase susceptibility to the diseases which the vaccines are supposed to prevent and also to a host of related and unrelated viral and bacterial infections. Vaccines are involved in a great number of modern ills of childhood such as immunoreactive diseases (asthma, allergies), autoimmune diseases (diabetes, multiple sclerosis, lupus erythematosis), cancers, leukaemia, degenerative diseases of bone and cartilage, behavioural and learning problems, to mention just the most important conditions.

Her research into vaccination has culminated so far in two books and a number of shorter and longer individual papers published in a variety of scientific and medical publications. She has also conducted frequent international lecture tours to present the results of her research to parents, health and medical professionals and anyone else who is interested. She has also provided a great number of expert witness reports for court cases relating to deaths and injuries caused by vaccines, such as so-called “shaken baby” syndrome.

Narcolepsy diagnosis in Sweden and Finland

 

Emelie Olsson falls asleep as he watches television in her apartment in Stockholm, January 17, 2013. Emelie is one of around 800 children in Sweden and elsewhere in Europe who developed narcolepsy, an incurable sleep disorder, after being immunised in 2009 with the Pandemrix H1N1 swine flu vaccine made by British drugmaker GlaxoSmithKline. Picture taken January 17, 2013. REUTERS-Ints Kalnins
Emelie Olsson shows her paintings in Stockholm January 17, 2013. REUTERS-Ints Kalnins
The first shipment of pandemic vaccine against the swine influenza A (H1N1) Pandemrix arrives in Malmo in this October 9, 2009 file photo. REUTERS-Scanpix

By Kate Kelland, Health and Science Correspondent

STOCKHOLM | Tue Jan 22, 2013 7:26am EST

(Reuters) – Emelie Olsson is plagued by hallucinations and nightmares. When she wakes up, she’s often paralyzed, unable to breathe properly or call for help. During the day she can barely stay awake, and often misses school or having fun with friends. She is only 14, but at times she has wondered if her life is worth living.

Emelie is one of around 800 children in Sweden and elsewhere in Europe who developed narcolepsy, an incurable sleep disorder, after being immunized with the Pandemrix H1N1 swine flu vaccine made by British drugmaker GlaxoSmithKline in 2009.

Finland, Norway, Ireland and France have seen spikes in narcolepsy cases, too, and people familiar with the results of a soon-to-be-published study in Britain have told Reuters it will show a similar pattern in children there.

Their fate, coping with an illness that all but destroys normal life, is developing into what the health official who coordinated Sweden’s vaccination campaign calls a “medical tragedy” that will demand rising scientific and medical attention.

Europe’s drugs regulator has ruled Pandemrix should no longer be used in people aged under 20. The chief medical officer at GSK’s vaccines division, Norman Begg, says his firm views the issue extremely seriously and is “absolutely committed to getting to the bottom of this”, but adds there is not yet enough data or evidence to suggest a causal link.

Others – including Emmanuel Mignot, one of the world’s leading experts on narcolepsy, who is being funded by GSK to investigate further – agree more research is needed but say the evidence is already clearly pointing in one direction.

“There’s no doubt in my mind whatsoever that Pandemrix increased the occurrence of narcolepsy onset in children in some countries – and probably in most countries,” says Mignot, a specialist in the sleep disorder at Stanford University in the United States.

30 MILLION RECEIVED PANDEMRIX

In total, the GSK shot was given to more than 30 million people in 47 countries during the 2009-2010 H1N1 swine flu pandemic. Because it contains an adjuvant, or booster, it was not used in the United States because drug regulators there are wary of adjuvanted vaccines.

GSK says 795 people across Europe have reported developing narcolepsy since the vaccine’s use began in 2009.

Questions about how the narcolepsy cases are linked to Pandemrix, what the triggers and biological mechanisms might have been, and whether there might be a genetic susceptibility are currently the subject of deep scientific investigation.

But experts on all sides are wary. Rare adverse reactions can swiftly develop into “vaccine scares” that spiral out of proportion and cast what one of Europe’s top flu experts calls a “long shadow” over public confidence in vaccines that control potential killers like measles and polio.

“No-one wants to be the next Wakefield,” said Mignot, referring to the now discredited British doctor Andrew Wakefield who sparked a decades-long backlash against the measles, mumps and rubella (MMR) shot with false claims of links to autism.

With the narcolepsy studies, there is no suggestion that the findings are the work of one rogue doctor.

Independent teams of scientists have published peer-reviewed studies from Sweden, Finland and Ireland showing the risk of developing narcolepsy after the 2009-2010 immunization campaign was between seven and 13 times higher for children who had Pandemrix than for their unvaccinated peers.

“We really do want to get to the bottom of this. It’s not in anyone’s interests if there is a safety issue that needs to be addressed,” said GSK’s Begg.

LIFE CHANGED

Emelie’s parents, Charles and Marie Olsson, say she was a top student who loved playing the piano, taking tennis lessons, creating art and having fun with friends. But her life started to change in early 2010, a few months after she had Pandemrix. In the spring of 2010, they noticed she was often tired, needing to sleep when she came home from school.

But it wasn’t until May, when she began collapsing at school, that it became clear something serious was happening.

As well as the life-limiting bouts of daytime sleepiness, narcolepsy brings nightmares, hallucinations, sleep paralysis and episodes of cataplexy – when strong emotions trigger a sudden and dramatic loss of muscle strength.

In Emelie’s case, having fun is the emotional trigger. “I can’t laugh or joke about with my friends any more, because when I do I get cataplexies and collapse,” she said in an interview at her home in the Swedish capital.

Narcolepsy is estimated to affect between 200 and 500 people per million and is a lifelong condition. It has no known cure and scientists don’t really know what causes it. But they do know patients have a deficit of a brain neurotransmitter called orexin, also known as hypocretin, which regulates wakefulness.

Research has found that some people are born with a variant in a gene known as HLA that means they have low hypocretin, making them more susceptible to narcolepsy. Around 25 percent of Europeans are thought to have this genetic vulnerability.

When results of Emelie’s hypocretin test came back in November last year, it showed she had 15 percent of the normal amount, typical of heavy narcolepsy with cataplexy.

The seriousness of her strange new illness has forced her to contemplate life far more than many other young teens: “In the beginning I didn’t really want to live any more, but now I have learned to handle things better,” she said.

TRIGGERS?

Scientists investigating these cases are looking in detail at Pandemrix’s adjuvant, called AS03, for clues.

Some suggest AS03, or maybe its boosting effect, or even the H1N1 flu itself, may have triggered the onset of narcolepsy in those who have the susceptible HLA gene variant.

Angus Nicoll, a flu expert at the European Centre for Disease Prevention and Control (ECDC), says genes may well play a part, but don’t tell the whole story.

“Yes, there’s a genetic predisposition to this condition, but that alone cannot explain these cases,” he said. “There was also something to do with receiving this specific vaccination. Whether it was the vaccine plus the genetic disposition alone or a third factor as well – like another infection – we simply do not know yet.”

GSK is funding a study in Canada, where its adjuvanted vaccine Arepanrix, similar to Pandemrix, was used during the 2009-2010 pandemic. The study won’t be completed until 2014, and some experts fear it may not shed much light since the vaccines were similar but not precisely the same.

It all leaves this investigation with far more questions than answers, and a lot more research ahead.

WAS IT WORTH IT?

In his glass-topped office building overlooking the Maria Magdalena church in Stockholm, Goran Stiernstedt, a doctor turned public health official, has spent many difficult hours going over what happened in his country during the swine flu pandemic, wondering if things should have been different.

“The big question is was it worth it? And retrospectively I have to say it was not,” he told Reuters in an interview.

Being a wealthy country, Sweden was at the front of the queue for pandemic vaccines. It got Pandemrix from GSK almost as soon as it was available, and a nationwide campaign got uptake of the vaccine to 59 percent, meaning around 5 million people got the shot.

Stiernstedt, director for health and social care at the Swedish Association of Local Authorities and Regions, helped coordinate the vaccination campaign across Sweden’s 21 regions.

The World Health Organisation (WHO) says the 2009-2010 pandemic killed 18,500 people, although a study last year said that total might be up to 15 times higher.

While estimates vary, Stiernstedt says Sweden’s mass vaccination saved between 30 and 60 people from swine flu death. Yet since the pandemic ended, more than 200 cases of narcolepsy have been reported in Sweden.

With hindsight, this risk-benefit balance is unacceptable. “This is a medical tragedy,” he said. “Hundreds of young people have had their lives almost destroyed.”

PANDEMICS ARE EMERGENCIES

Yet the problem with risk-benefit analyses is that they often look radically different when the world is facing a pandemic with the potential to wipe out millions than they do when it has emerged relatively unscathed from one, like H1N1, which turned out to be much milder than first feared.

David Salisbury, the British government’s director of immunization, says “therein lies the risk, and the difficulty, of working in public health” when a viral emergency hits.

“In the event of a severe pandemic, the risk of death is far higher than the risk of narcolepsy,” he told Reuters. “If we spent longer developing and testing the vaccine on very large numbers of people and waited to see whether any of them developed narcolepsy, much of the population might be dead.”

Pandemrix was authorized by European drug regulators using a so-called “mock-up procedure” that allows a vaccine to be authorized ahead of a possible pandemic using another flu strain. In Pandemrix’s case, the substitute was H5N1 bird flu.

When the WHO declared a pandemic, GSK replaced the mock-up’s strain with the pandemic-causing H1N1 strain to form Pandemrix.

GSK says the final H1N1 version was tested in trials involving around 3,600 patients, including children, adolescents, adults and the elderly, before it was rolled out.

The ECDC’s Nicoll says early warning systems that give a more accurate analysis of a flu strain’s threat are the best way to minimize risks of this kind of tragedy happening in future.

Salisbury agrees, and says progress towards a universal flu vaccine – one that wouldn’t need last-minute changes made when a new strain emerged – would cuts risks further.

“Ideally, we would have a better vaccine that would work against all strains of influenza and we wouldn’t need to worry about this ever again,” he said. “But that’s a long way off.”

With scientists facing years of investigation and research, Emelie just wants to make the best of her life.

She reluctantly accepts that to do so, she needs a cocktail of drugs to try to control the narcolepsy symptoms. The stimulant Ritalin and the sleeping pill Sobril are prescribed for Emelie’s daytime sleepiness and night terrors. Then there’s Prozac to try to stabilize her and limit her cataplexies.

“That’s one of the things that makes me feel most uncomfortable,” she explains. “Before I got this condition I didn’t take any pills, and now I have to take lots – maybe for the rest of my life. It’s not good to take so many medicines, especially when you know they have side effects.”

Regulators Discover a Hidden Viral Gene in Commercial GMO Crops

January 21, 2013 Biotechnology, Commentaries 8 Comments

by Jonathan Latham and Allison Wilson

How should a regulatory agency announce they have discovered something potentially very important about the safety of products they have been approving for over twenty years?

In the course of analysis to identify potential allergens in GMO crops, the European Food Safety Authority (EFSA) has belatedly discovered that the most common genetic regulatory sequence in commercial GMOs also encodes a significant fragment of a viral gene (Podevin and du Jardin 2012). This finding has serious ramifications for crop biotechnology and its regulation, but possibly even greater ones for consumers and farmers. This is because there are clear indications that this viral gene (called Gene VI) might not be safe for human consumption. It also may disturb the normal functioning of crops, including their natural pest resistance.

Cauliflower Mosaic Virus

Cauliflower Mosaic Virus

What Podevin and du Jardin discovered is that of the 86 different transgenic events (unique insertions of foreign DNA) commercialized to-date in the United States 54 contain portions of Gene VI within them. They include any with a widely used gene regulatory sequence called the CaMV 35S promoter (from the cauliflower mosaic virus; CaMV). Among the affected transgenic events are some of the most widely grown GMOs, including Roundup Ready soybeans (40-3-2) and MON810 maize. They include the controversial NK603 maize recently reported as causing tumors in rats (Seralini et al. 2012).

The researchers themselves concluded that the presence of segments of Gene VI “might result in unintended phenotypic changes”. They reached this conclusion because similar fragments of Gene VI have already been shown to be active on their own (e.g. De Tapia et al. 1993). In other words, the EFSA researchers were unable to rule out a hazard to public health or the environment.

In general, viral genes expressed in plants raise both agronomic and human health concerns (reviewed in Latham and Wilson 2008). This is because many viral genes function to disable their host in order to facilitate pathogen invasion. Often, this is achieved by incapacitating specific anti-pathogen defenses. Incorporating such genes could clearly lead to undesirable and unexpected outcomes in agriculture. Furthermore, viruses that infect plants are often not that different from viruses that infect humans. For example, sometimes the genes of human and plant viruses are interchangeable, while on other occasions inserting plant viral fragments as transgenes has caused the genetically altered plant to become susceptible to an animal virus (Dasgupta et al. 2001). Thus, in various ways, inserting viral genes accidentally into crop plants and the food supply confers a significant potential for harm.

The Choices for Regulators
The original discovery by Podevin and du Jardin (at EFSA) of Gene VI in commercial GMO crops must have presented regulators with sharply divergent procedural alternatives. They could 1) recall all CaMV Gene VI-containing crops (in Europe that would mean revoking importation and planting approvals) or, 2) undertake a retrospective risk assessment of the CaMV promoter and its Gene VI sequences and hope to give it a clean bill of health.

It is easy to see the attraction for EFSA of option two. Recall would be a massive political and financial decision and would also be a huge embarrassment to the regulators themselves. It would leave very few GMO crops on the market and might even mean the end of crop biotechnology.

Regulators, in principle at least, also have a third option to gauge the seriousness of any potential GMO hazard. GMO monitoring, which is required by EU regulations, ought to allow them to find out if deaths, illnesses, or crop failures have been reported by farmers or health officials and can be correlated with the Gene VI sequence. Unfortunately, this particular avenue of enquiry is a scientific dead end. Not one country has carried through on promises to officially and scientifically monitor any hazardous consequences of GMOs (1).

Unsurprisingly, EFSA chose option two. However, their investigation resulted only in the vague and unreassuring conclusion that Gene VI “might result in unintended phenotypic changes” (Podevin and du Jardin 2012). This means literally, that changes of an unknown number, nature, or magnitude may (or may not) occur. It falls well short of the solid scientific reassurance of public safety needed to explain why EFSA has not ordered a recall.

Can the presence of a fragment of virus DNA really be that significant? Below is an independent analysis of Gene VI and its known properties and their safety implications. This analysis clearly illustrates the regulators’ dilemma.

The Many Functions of Gene VI
Gene VI, like most plant viral genes, produces a protein that is multifunctional. It has four (so far) known roles in the viral infection cycle. The first is to participate in the assembly of virus particles. There is no current data to suggest this function has any implications for biosafety. The second known function is to suppress anti-pathogen defenses by inhibiting a general cellular system called RNA silencing (Haas et al. 2008). Thirdly, Gene VI has the highly unusual function of transactivating (described below) the long RNA (the 35S RNA) produced by CaMV (Park et al. 2001). Fourthly, unconnected to these other mechanisms, Gene VI has very recently been shown to make plants highly susceptible to a bacterial pathogen (Love et al. 2012). Gene VI does this by interfering with a common anti-pathogen defense mechanism possessed by plants. These latter three functions of Gene VI (and their risk implications) are explained further below:

1) Gene VI Is an Inhibitor of RNA Silencing
RNA silencing is a mechanism for the control of gene expression at the level of RNA abundance (Bartel 2004). It is also an important antiviral defense mechanism in both plants and animals, and therefore most viruses have evolved genes (like Gene VI) that disable it (Dunoyer and Voinnet 2006).

Cauliflower mosaic virus genome

Gene VI (upper left) precedes the start of the 35S RNA

This attribute of Gene VI raises two obvious biosafety concerns: 1) Gene VI will lead to aberrant gene expression in GMO crop plants, with unknown consequences and, 2) Gene VI will interfere with the ability of plants to defend themselves against viral pathogens. There are numerous experiments showing that, in general, viral proteins that disable gene silencing enhance infection by a wide spectrum of viruses (Latham and Wilson 2008).

2) Gene VI Is a Unique Transactivator of Gene Expression
Multicellular organisms make proteins by a mechanism in which only one protein is produced by each passage of a ribosome along a messenger RNA (mRNA). Once that protein is completed the ribosome dissociates from the mRNA. However, in a CaMV-infected plant cell, or as a transgene, Gene VI intervenes in this process and directs the ribosome to get back on an mRNA (reinitiate) and produce the next protein in line on the mRNA, if there is one. This property of Gene VI enables Cauliflower Mosaic Virus to produce multiple proteins from a single long RNA (the 35S RNA). Importantly, this function of Gene VI (which is called transactivation) is not limited to the 35S RNA. Gene VI seems able to transactivate any cellular mRNA (Futterer and Hohn 1991; Ryabova et al. 2002). There are likely to be thousands of mRNA molecules having a short or long protein coding sequence following the primary one. These secondary coding sequences could be expressed in cells where Gene VI is expressed. The result will presumably be production of numerous random proteins within cells. The biosafety implications of this are difficult to assess. These proteins could be allergens, plant or human toxins, or they could be harmless. Moreover, the answer will differ for each commercial crop species into which Gene VI has been inserted.

3) Gene VI Interferes with Host Defenses
A very recent finding, not known by Podevin and du Jardin, is that Gene VI has a second mechanism by which it interferes with plant anti-pathogen defenses (Love et al. 2012). It is too early to be sure about the mechanistic details, but the result is to make plants carrying Gene VI more susceptible to certain pathogens, and less susceptible to others. Obviously, this could impact farmers, however the discovery of an entirely new function for gene VI while EFSA’s paper was in press, also makes clear that a full appraisal of all the likely effects of Gene VI is not currently achievable.

Is There a Direct Human Toxicity Issue?
When Gene VI is intentionally expressed in transgenic plants, it causes them to become chlorotic (yellow), to have growth deformities, and to have reduced fertility in a dose-dependent manner (Ziljstra et al 1996). Plants expressing Gene VI also show gene expression abnormalities. These results indicate that, not unexpectedly given its known functions, the protein produced by Gene VI is functioning as a toxin and is harmful to plants (Takahashi et al 1989). Since the known targets of Gene VI activity (ribosomes and gene silencing) are also found in human cells, a reasonable concern is that the protein produced by Gene VI might be a human toxin. This is a question that can only be answered by future experiments.

Is Gene VI Protein Produced in GMO Crops?
Given that expression of Gene VI is likely to cause harm, a crucial issue is whether the actual inserted transgene sequences found in commercial GMO crops will produce any functional protein from the fragment of Gene VI present within the CaMV sequence.

There are two aspects to this question. One is the length of Gene VI accidentally introduced by developers. This appears to vary but most of the 54 approved transgenes contain the same 528 base pairs of the CaMV 35S promoter sequence. This corresponds to approximately the final third of Gene VI. Deleted fragments of Gene VI are active when expressed in plant cells and functions of Gene VI are believed to reside in this final third. Therefore, there is clear potential for unintended effects if this fragment is expressed (e.g. De Tapia et al. 1993; Ryabova et al. 2002; Kobayashi and Hohn 2003).

The second aspect of this question is what quantity of Gene VI could be produced in GMO crops? Once again, this can ultimately only be resolved by direct quantitative experiments. Nevertheless, we can theorize that the amount of Gene VI produced will be specific to each independent insertion event. This is because significant Gene VI expression probably would require specific sequences (such as the presence of a gene promoter and an ATG [a protein start codon]) to precede it and so is likely to be heavily dependent on variables such as the details of the inserted transgenic DNA and where in the plant genome the transgene inserted.

Commercial transgenic crop varieties can also contain superfluous copies of the transgene, including those that are incomplete or rearranged (Wilson et al 2006). These could be important additional sources of Gene VI protein. The decision of regulators to allow such multiple and complex insertion events was always highly questionable, but the realization that the CaMV 35S promoter contains Gene VI sequences provides yet another reason to believe that complex insertion events increase the likelihood of a biosafety problem.

Even direct quantitative measurements of Gene VI protein in individual crop authorizations would not fully resolve the scientific questions, however. No-one knows, for example, what quantity, location or timing of protein production would be of significance for risk assessment, and so answers necessary to perform science-based risk assessment are unlikely to emerge soon.

Big Lessons for Biotechnology
It is perhaps the most basic assumption in all of risk assessment that the developer of a new product provides regulators with accurate information about what is being assessed. Perhaps the next most basic assumption is that regulators independently verify this information.  We now know, however, that for over twenty years neither of those simple expectations have been met. Major public universities, biotech multinationals, and government regulators everywhere, seemingly did not appreciate the relatively simple possibility that the DNA constructs they were responsible for encoded a viral gene.

This lapse occurred despite the fact that Gene VI was not truly hidden; the relevant information on the existence of Gene VI has been freely available in the scientific literature since well before the first biotech approval (Franck et al 1980). We ourselves have offered specific warnings that viral sequences could contain unsuspected genes (Latham and Wilson 2008). The inability of risk assessment processes to incorporate longstanding and repeated scientific findings is every bit as worrysome as the failure to intellectually anticipate the possibility of overlapping genes when manipulating viral sequences.

This sense of a generic failure is reinforced by the fact that this is not an isolated event. There exist other examples of commercially approved viral sequences having overlapping genes that were never subjected to risk assessment. These include numerous commercial GMOs containing promoter regions of the closely related virus figwort mosaic virus (FMV) which were not considered by Podevin and du Jardin. Inspection of commercial sequence data shows that the commonly used FMV promoter overlaps its own Gene VI (Richins et al 1987). A third example is the virus-resistant potato NewLeaf Plus (RBMT-22-82). This transgene contains approximately 90% of the P0 gene of potato leaf roll virus. The known function of this gene, whose existence was discovered only after US approval, is to inhibit the anti-pathogen defenses of its host (Pfeffer et al 2002). Fortunately, this potato variety was never actively marketed.

A further key point relates to the biotech industry and their campaign to secure public approval and a permissive regulatory environment. This has led them to repeatedly claim, firstly, that GMO technology is precise and predictable; and secondly, that their own competence and self-interest would prevent them from ever bringing potentially harmful products to the market; and thirdly, to assert that only well studied and fully understood transgenes are commercialized. It is hard to imagine a finding more damaging to these claims than the revelations surrounding Gene VI.

Biotechnology, it is often forgotten, is not just a technology. It is an experiment in the proposition that human institutions can perform adequate risk assessments on novel living organisms. Rather than treat that question as primarily a daunting scientific one, we should for now consider that the primary obstacle will be overcoming the much more mundane trap of human complacency and incompetence. We are not there yet, and therefore this incident will serve to reinforce the demands for GMO labeling in places where it is absent.

What Regulators Should Do Now
This summary of the scientific risk issues shows that a segment of a poorly characterized viral gene never subjected to any risk assessment (until now) was allowed onto the market. This gene is currently present in commercial crops and growing on a large scale. It is also widespread in the food supply.

Even now that EFSA’s own researchers have belatedly considered the risk issues, no one can say whether the public has been harmed, though harm appears a clear scientific possibility. Considered from the perspective of professional and scientific risk assessment, this situation represents a complete and catastrophic system failure.

But the saga of Gene VI is not yet over. There is no certainty that further scientific analysis will resolve the remaining uncertainties, or provide reassurance. Future research may in fact increase the level of concern or uncertainty, and this is a possibility that regulators should weigh heavily in their deliberations.

To return to the original choices before EFSA, these were either to recall all CaMV 35S promoter-containing GMOs, or to perform a retrospective risk assessment. This retrospective risk assessment has now been carried out and the data clearly indicate a potential for significant harm. The only course of action consistent with protecting the public and respecting the science is for EFSA, and other jurisdictions, to order a total recall. This recall should also include GMOs containing the FMV promoter and its own overlapping Gene VI.

Footnotes
1)  EFSA regulators might now be regretting their failure to implement meaningful GMO monitoring. It would be a good question for European politicians to ask EFSA and for the board of EFSA to ask the GMO panel, whose job it is to implement monitoring.

References
Bartel P (2004)  MicroRNAs: Genomics, Biogenesis, Mechanism, and Function. Cell: 116, 281-297.
Dasgupta R , Garcia BH,  Goodman RM (2001) Systemic spread of an RNA insect virus in plants expressing plant viral movement protein genes. Proc. Natl. Acad. Sci. USA 98: 4910-4915.

De Tapia M, Himmelbach A, and Hohn T (1993) Molecular dissection of the cauliflower mosaic virus translation transactivator. EMBO J 12: 3305-14.

Dunoyer P, and  O Voinnet (2006) The complex interplay between plant viruses and host RNA-silencing pathways.  Curr Opinion in Plant Biology 8: 415–423.

Franck A, H Guilley, G Jonard, K Richards and L Hirth (1980) Nucleotide sequence of cauliflower mosaic virus DNA. Cell 2: 285-294.
Futterer J, and T Hohn (1991) Translation of a polycistronic mRNA in presence of the cauliflower mosaic virus transactivator protein. EMBO J. 10: 3887-3896.

Haas G, Azevedo J, Moissiard G, Geldreich A, Himber C, Bureau M, et al. (2008) Nuclear import of CaMV P6 is required for infection and suppression of the RNA silencing factor DRB4. EMBO J 27: 2102-12.

Kobayashi K, and T Hohn (2003) Dissection of Cauliflower Mosaic Virus Transactivator/Viroplasmin Reveals Distinct Essential Functions in Basic Virus Replication. J. Virol. 77: 8577–8583.

Latham JR, and AK Wilson (2008) Transcomplementation and Synergism in Plants: Implications for Viral Transgenes? Molecular Plant Pathology 9: 85-103.

Park H-S, Himmelbach A, Browning KS, Hohn T, and Ryabova LA (2001). A plant viral ‘‘reinitiation’’ factor interacts with the host translational machinery. Cell 106: 723–733.

Pfeffer S, P Dunoyer, F Heim, KE Richards, G Jonard, V Ziegler-Graff (2002) P0 of Beet Western Yellows Virus Is a Suppressor of Posttranscriptional Gene Silencing. J. Virol. 76: 6815–6824.

Podevin N and  du Jardin P (2012) Possible consequences of the overlap between the CaMV 35S promoter regions in plant transformation vectors used and the viral gene VI in transgenic plants. GM Crops and Food 3: 1-5.

Love AJ , C Geri, J Laird, C Carr, BW Yun, GJ Loake et al (2012) Cauliflower mosaic virus Protein P6 Inhibits Signaling Responses to Salicylic Acid and Regulates Innate Immunity. PLoS One. 7(10): e47535.

Richins R, H Scholthof, RJ Shepherd (1987) Sequence of figwort mosaic virus DNA (caulimovirus group). NAR 15: 8451-8466.

Ryabova LA , Pooggin, MH and Hohn, T (2002) Viral strategies of translation initiation: Ribosomal shunt and reinitiation. Progress in Nucleic Acid Research and Molecular Biology 72: 1-39.

Séralini, G-E., E. Clair, R. Mesnage, S. Gress, N. Defarge, M. Malatesta, D. Hennequin, J. Spiroux de Vendômois. 2012. Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food Chem. Toxicol.

Takahashi H, K Shimamoto, Y Ehara (1989) Cauliflower mosaic virus gene VI causes growth suppression, development of necrotic spots and expression of defence-related genes in transgenic tobacco plants. Molecular and General Genetics 216:188-194.

Wilson AK, JR Latham and RA Steinbrecher (2006) Transformation-induced mutations in transgenic plants: Analysis and biosafety implications. Biotechnology and Genetic Engineering Reviews 23: 209-234.

Zijlstra C, Schärer-Hernández N, Gal S, Hohn T. Arabidopsis thaliana expressing the cauliflower mosaic virus ORF VI transgene has a late flowering phenotype. Virus Genes 1996; 13:5-17.

This vaccine regime is being made mandatory all over the world.

Vaccinated Children Have More Than Twice the Diseases and Disorders Than Unvaccinated Children

50-Reasons-NOT-to-Vaccinate-your-Children1This survey was A German study released in September 2011 of about 8000 UNVACCINATED children, newborn to 19 years, show vaccinated children have more than twice the diseases and disorders than unvaccinated children.

The results are presented in the bar chart below; the complete data and study results are here. The data is compared to the national German KIGGS health study of the children in the general population. Most of the respondents to the survey were from the U.S. (Click on the chart to see it better)


Salzburger Study

Results: of 1004 unvaccinated children, had

Asthma, 0% (8-12% in the normal population)

A-topic dermatitis 1.2% (10-20% in the normal population)

Allergies 3% (25% in the normal population)

ADHD 0.79% (5-10%) in children

Longterm Study in Guinea-Bissau (1 Kristensen I, Aaby P, Jensen H.:“Routine vaccinations and child survival: follow up study in Guinea-Bissau, West Africa”, BMJ 2000; 321: 1435–41)

The children of 15,000 mothers were observed from 1990 to 1996 for 5 years.

Result: the death rate in vaccinated children against diphtheria, tetanus and whooping cough is twice as high as the unvaccinated children (10.5% versus 4.7%).

New Zealand Survey (1992) (http://www.ias.org.nz)

The study involved 254 children. In which 133 children were vaccinated and 121 remained unvaccinated.

Result:

Symptom vaccinated unvaccinated
Asthma 20 (15%) 4 (3%)
Eczema or allergic rashes 43 (32%) 16 (13%)
Chronic otitis 26 (20%) 8 (7%)
Recurrent tonsillitis 11 (8%) 3 (2%)
Shortness of breath and sudden infant death syndrome 9 (7%) 2 (2%)
Hyperactivity 10 (8%) 1 (1%)

 

 

 

 

Download and read the IAS1992study now.

Why do the Medical Profession lie about Vaccines?

Advance Notice on U.S Vaccination Survey / German Study: Vaccinated Children Have More Than Twice the Diseases and Disorders Than Unvaccinated Children

Posted on October 9, 2011 by augie

 

This survey was A German study released in September 2011 of about 8000 UNVACCINATED children, newborn to 19 years, show vaccinated children have more than twice the diseases and disorders than unvaccinated children.

The results are presented in the bar chart below; the complete data and study results are here. The data is compared to the national German KIGGS health study of the children in the general population. Most of the respondents to the survey were from the U.S. (Click on the chart to see it better)


Salzburger Study

Results: of 1004 unvaccinated children, had

Asthma, 0% (8-12% in the normal population)

A-topic dermatitis 1.2% (10-20% in the normal population)

Allergies 3% (25% in the normal population)

ADHD 0.79% (5-10%) in children

Longterm Study in Guinea-Bissau (1 Kristensen I, Aaby P, Jensen H.:“Routine vaccinations and child survival: follow up study in Guinea-Bissau, West Africa”, BMJ 2000; 321: 1435–41)

The children of 15,000 mothers were observed from 1990 to 1996 for 5 years.

Result: the death rate in vaccinated children against diphtheria, tetanus and whooping cough is twice as high as the unvaccinated children (10.5% versus 4.7%).

New Zealand Survey (1992) (http://www.ias.org.nz)

The study involved 254 children. In which 133 children were vaccinated and 121 remained unvaccinated.

Result:

Symptom vaccinated unvaccinated
Asthma 20 (15%) 4 (3%)
Eczema or allergic rashes 43 (32%) 16 (13%)
Chronic otitis 26 (20%) 8 (7%)
Recurrent tonsillitis 11 (8%) 3 (2%)
Shortness of breath and sudden infant death syndrome 9 (7%) 2 (2%)
Hyperactivity 10 (8%) 1 (1%)

 

 

TriHealth fires 150 employees for not getting flu shots

Company offered the shots for free

UPDATED 2:09 PM EST Nov 22, 2012

CINCINNATI —One of Cincinnati’s largest employers fired approximately 150 employees Wednesday for failing to get a required flu shot.

TriHealth offered all of its 10,800 employees free flu shots. Employees had a month to get the flu shot. The deadline was Nov. 16. Employees who did not get the shot were terminated Wednesday, a company spokesperson said.

Employees who were terminated can appeal to be reinstated after receiving the shot.

Read more: http://www.wlwt.com/news/local-news/cincinnati/TriHealth-fires-150-employees-for-not-getting-flu-shots/-/13549970/17523386/-/3khe3s/-/index.html#ixzz2DK1zilMa

Bad Behavior has blocked 4997 access attempts in the last 7 days.